25518-15-4

Basic information

• Product Name: 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline
• Synonyms: 2-(5-phenyl-1H-1,2,4-triazol-3-yl)aniline; benzenamine, 2-(5-phenyl-1H-1,2,4-triazol-3-yl)-
• CAS NO: 25518-15-4
• Molecular Formula: C₁₄H₁₂N₄
• Molecular Weight: 236.2719
• Mol File: 25518-15-4.mol

Chemical Properties

• Boiling Point: 500.808°C at 760 mmHg
• Flash Point: 288.997°C
• Density: 1.263g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.675
• CAS DataBase Reference: 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline(25518-15-4)
• EPA Substance Registry System: 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline(25518-15-4)

Safety Data

• Hazardous Substances Data: 25518-15-4(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline is used as a building block in chemical synthesis for the development of a range of organic compounds. Its unique structure, which includes a phenyl group, triazole ring, and aniline moiety, allows for the creation of diverse chemical entities with potential applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline is used as a precursor or intermediate in the synthesis of pharmaceutical compounds. Its presence in these compounds can contribute to their biological activity, making it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 2-(3-phenyl-1H-1,2,4-triazol-5-yl)aniline is employed as a component in the formulation of agrochemical products. Its incorporation can enhance the effectiveness of these products, such as pesticides or herbicides, by improving their stability, solubility, or target specificity.

Upstream product

• 153488-31-4 2-benzhydrazide 
• 58314-88-8 N-ethoxymethylene-2-aminobenzonitrile 
• 613-94-5 benzoic acid hydrazide 
• 153488-27-8 3-benzoylamino-4-imino-3,4-dihydroquinazoline 
• 1885-29-6 anthranilic acid nitrile 
• 1670-14-0 benzamidine monohydrochloride 
• 1904-58-1 anthranilic acid hydrazide 
• 118-48-9 isatoic anhydride 
• 74222-83-6 benzamidine hydrochloride hydrate 

Downstream Products

• 130408-02-5 2-phenyl<1,2,4>triazolo<1,5-c>quinazoline 
• 61330-43-6 2,5-diphenyl<1,2,4>triazolo<1,5-c>quinazoline 

Relevant articles and documents

Synthesis of diverse azolo[c]quinazolines by palladium(II)- catalyzed aerobic oxidative insertion of isocyanides

We report the palladium(II)-catalyzed aerobic oxidative coupling of isocyanides with various (2-aminophenyl)azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo[c]quinazolines was obtained by this new approach.

Synthesis of Triazoloquinazoline and Triazolo-1,4-benzodiazepine Derivatives

Some triazoloquinazolin-5(6H)-ones 7, the corresponding isomers triazoloquinazolin-5(6H)-ones and the 5-amino derivatives 8,9 and 11 have been synthesized starting from the acylamidrazones 5.The preparation of 5H-triazol

A CONVENIENT SYNTHESIS OF 3,5-DISUBSTITUED-1,2,4-TRIAZOLES

The condensation of an acyl hydrazide and an amidine to afford an acylamidrazone, followed by thermal cyclization, provides a convenient method for preparing 3,5-disubstitued-1,2,4-triazoles in high yields.