- Monodisperse CuPd alloy nanoparticles as efficient and reusable catalyst for the C (sp2)–H bond activation
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Metal-catalyzed selective activation of C–H bonds is very important for the construction of a variety of biologically active molecules. Supported alloy nanoparticles are of great interest in various catalytic applications due to the synergistic effects between different metals. Here, well-dispersed CuPd alloy nanoparticles supported on reduced graphene oxide (rGO) were synthesized and found to be highly efficient and recyclable catalyst for the chelation-assisted C (sp2)–H bond activation. Aromatic ketones or esters were synthesized via the cross-dehydrogenative coupling (CDC) reaction between 2-arylpyridines and alcohols or acids. Moreover, the catalyst was recovered and used for five times without significantly losing activity.
- Huang, Fei,Wang, Feifan,Hu, Qiyan,Tang, Lin,Xu, Dongping,Fang, Yang,Zhang, Wu
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- Rhodium-Catalyzed Dealkenylative Arylation of Alkenes with Arylboronic Compounds
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The C?C bond formation reaction represents a fundamental and important transformation in synthetic chemistry, and exploring new types of C?C bond formation reactions is recognized as appealing, yet challenging. Herein, we disclose the first example of rhodium-catalyzed dealkenylative arylation of alkenes with arylboronic compounds, thereby providing an unconventional access to bi(hetero)aryls with excellent chemoselectivity. In this method, C(aryl)?C(alkenyl) and C(alkenyl)?C(alkenyl) bonds in various alkenes and 1,3-dienes can be cleaved via a hydrometalation and followed by β-carbon elimination pathway for Suzuki–Miyaura reactions. Furthermore, a series of novel organic fluorescent molecules with excellent photophysical properties has been efficiently constructed with this protocol.
- Das, Mowpriya,Glorius, Frank,Maisuls, Iván,Strassert, Cristian A.,Tan, Guangying
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supporting information
p. 15650 - 15655
(2021/06/08)
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- Catalytic, Directed C-C Bond Functionalization of Styrenes
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A method for catalytic conversion of C(aryl)-C(alkenyl) bonds in styrene derivatives to new C-C bonds is developed. In the presence of a rhodium catalyst, the alkenyl groups of styrenes bearing a pyrazolyl directing group were efficiently converted to other carbon substituents upon reacting with various alkenes including styrenes, aliphatic alkenes, and allyl alcohols. It is also indicated that the C-C bond cleavage proceeded via a hydrometalation/β-carbon elimination pathway.
- Onodera, Shunsuke,Togashi, Ryo,Ishikawa, Soya,Kochi, Takuya,Kakiuchi, Fumitoshi
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supporting information
p. 7345 - 7349
(2020/08/19)
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- Manganese-Catalyzed Direct Nucleophilic C(sp2)-H Addition to Aldehydes and Nitriles
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Herein, a manganese-catalyzed nucleophilic addition of inert C(sp2)-H bonds to aldehydes and nitriles is disclosed by virtue of a dual activation strategy. The reactions feature mild reaction conditions, excellent regio- and stereoselectivity, and a wide substrate scope, which includes both aromatic and olefinic C-H bonds, as well as a large variety of aldehydes and nitriles. Moreover, mechanistic studies shed light on possible catalytic cycles.
- Zhou, Bingwei,Hu, Yuanyuan,Wang, Congyang
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supporting information
p. 13659 - 13663
(2015/11/16)
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- Ruthenium-catalyzed C-H functionalization of arylpyrazoles: Regioselective acylation with acid chlorides
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A ruthenium-catalyzed C-H acylation of arylpyrazoles with a variety of acyl chlorides is described. The acylation reaction exhibits good regioselectivity and both aromatic and aliphatic acyl chlorides can be effectively coupled to the arylpyrazoles at the
- Liu, Po Man,Frost, Christopher G.
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supporting information
p. 5862 - 5865
(2013/12/04)
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- Cyclization Reactions in Azole Chemistry: The Reaction of Some Azoles with o-Fluoroacetophenone, o-Fluorobenzaldehyde and o-Fluorobenzophenone
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The reactions of some azoles with o-fluoro-acetophenone, -benzaldehyde and -benzophenone in dimethyl sulfoxide solution in the presence of anhydrous potassium carbonate have been investigated.In addition to the expected substitution products, cyclization
- Rosevear, Judi,Wilshire, John F. K.
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p. 1097 - 1114
(2007/10/02)
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- REACTION OF 2-BROMO-2,3-DIHYDRO-1H-PYRAZOLOINDAZOLIUM BROMIDES WITH ALKALINE SOLUTION
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Treatment of 2-bromo-2,3-dihydro-1H-pyrazoloindazolium bromides (1a-c) with alkaline solution initially affords 9H-pyrazoloindazolium bromides (2a-c), which are further convertible by dehydrobromination into pyrazoloindazoles (3a-c>.T
- Fujimura, Yasuo,Nawata, Yoshiharu,Hamana, Masatomo
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p. 2771 - 2775
(2007/10/02)
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