25699-96-1

Usage

Uses

Used in Pharmaceutical Research:
Ethanone, 1-[2-(1H-pyrazol-1-yl)phenyl]is used as a research compound for the development of new drugs targeting specific receptors or biological pathways. Its unique molecular structure may offer novel therapeutic opportunities in various medical fields.
Used in Scientific Studies:
In scientific studies, Ethanone, 1-[2-(1H-pyrazol-1-yl)phenyl]serves as a reagent or intermediate in the synthesis of other compounds. Its properties and reactivity can be explored to understand its potential applications and interactions with other molecules.
Used in Chemical Synthesis:
Ethanone, 1-[2-(1H-pyrazol-1-yl)phenyl]is used as an intermediate in the synthesis of various chemical compounds. Its unique structure and reactivity make it a valuable component in the development of new chemical entities with potential applications in various industries.
Used in Drug Development:
In the pharmaceutical industry, Ethanone, 1-[2-(1H-pyrazol-1-yl)phenyl]is used as a key component in the development of new drugs. Its potential to target specific receptors or biological pathways may lead to the discovery of innovative therapeutic agents for the treatment of various diseases and conditions.
Further studies are needed to fully understand the properties and potential uses of Ethanone, 1-[2-(1H-pyrazol-1-yl)phenyl]-, and to explore its applications in different industries. Its unique molecular structure and reactivity may offer new opportunities for research and development in the fields of chemistry, pharmaceuticals, and other related disciplines.

Upstream product

• 1126-00-7 1-phenylpyrazole 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 87488-84-4 1-(2-bromophenyl)pyrazole 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 288-13-1 NH-pyrazole 
• 445-27-2 2'-Fluoroacetophenone 

Relevant academic research and scientific papers

Monodisperse CuPd alloy nanoparticles as efficient and reusable catalyst for the C (sp2)–H bond activation

Metal-catalyzed selective activation of C–H bonds is very important for the construction of a variety of biologically active molecules. Supported alloy nanoparticles are of great interest in various catalytic applications due to the synergistic effects between different metals. Here, well-dispersed CuPd alloy nanoparticles supported on reduced graphene oxide (rGO) were synthesized and found to be highly efficient and recyclable catalyst for the chelation-assisted C (sp2)–H bond activation. Aromatic ketones or esters were synthesized via the cross-dehydrogenative coupling (CDC) reaction between 2-arylpyridines and alcohols or acids. Moreover, the catalyst was recovered and used for five times without significantly losing activity.

Rhodium-Catalyzed Dealkenylative Arylation of Alkenes with Arylboronic Compounds

The C?C bond formation reaction represents a fundamental and important transformation in synthetic chemistry, and exploring new types of C?C bond formation reactions is recognized as appealing, yet challenging. Herein, we disclose the first example of rhodium-catalyzed dealkenylative arylation of alkenes with arylboronic compounds, thereby providing an unconventional access to bi(hetero)aryls with excellent chemoselectivity. In this method, C(aryl)?C(alkenyl) and C(alkenyl)?C(alkenyl) bonds in various alkenes and 1,3-dienes can be cleaved via a hydrometalation and followed by β-carbon elimination pathway for Suzuki–Miyaura reactions. Furthermore, a series of novel organic fluorescent molecules with excellent photophysical properties has been efficiently constructed with this protocol.

Catalytic, Directed C-C Bond Functionalization of Styrenes

A method for catalytic conversion of C(aryl)-C(alkenyl) bonds in styrene derivatives to new C-C bonds is developed. In the presence of a rhodium catalyst, the alkenyl groups of styrenes bearing a pyrazolyl directing group were efficiently converted to other carbon substituents upon reacting with various alkenes including styrenes, aliphatic alkenes, and allyl alcohols. It is also indicated that the C-C bond cleavage proceeded via a hydrometalation/β-carbon elimination pathway.

Manganese-Catalyzed Direct Nucleophilic C(sp2)-H Addition to Aldehydes and Nitriles

Herein, a manganese-catalyzed nucleophilic addition of inert C(sp2)-H bonds to aldehydes and nitriles is disclosed by virtue of a dual activation strategy. The reactions feature mild reaction conditions, excellent regio- and stereoselectivity, and a wide substrate scope, which includes both aromatic and olefinic C-H bonds, as well as a large variety of aldehydes and nitriles. Moreover, mechanistic studies shed light on possible catalytic cycles.

Ruthenium-catalyzed C-H functionalization of arylpyrazoles: Regioselective acylation with acid chlorides

A ruthenium-catalyzed C-H acylation of arylpyrazoles with a variety of acyl chlorides is described. The acylation reaction exhibits good regioselectivity and both aromatic and aliphatic acyl chlorides can be effectively coupled to the arylpyrazoles at the

Cyclization Reactions in Azole Chemistry: The Reaction of Some Azoles with o-Fluoroacetophenone, o-Fluorobenzaldehyde and o-Fluorobenzophenone

The reactions of some azoles with o-fluoro-acetophenone, -benzaldehyde and -benzophenone in dimethyl sulfoxide solution in the presence of anhydrous potassium carbonate have been investigated.In addition to the expected substitution products, cyclization

REACTION OF 2-BROMO-2,3-DIHYDRO-1H-PYRAZOLOINDAZOLIUM BROMIDES WITH ALKALINE SOLUTION

Treatment of 2-bromo-2,3-dihydro-1H-pyrazoloindazolium bromides (1a-c) with alkaline solution initially affords 9H-pyrazoloindazolium bromides (2a-c), which are further convertible by dehydrobromination into pyrazoloindazoles (3a-c>.T