Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
Genetic polymorphisms in CYP2C8 can influence the metabolism of important therapeutic agents and cause interindividual variation in drug response and toxicity. The significance of the variant CYP2C8*3 has been controversial with reports of higher in vivo
Kaspera, Ruediger,Naraharisetti, Suresh B.,Evangelista, Eric A.,Marciante, Kristin D.,Psaty, Bruce M.,Totah, Rheem A.
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p. 681 - 691
(2012/03/26)
Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation
A method for reducing post-ischaemic injury of the heart and/or improving the functional recovery of the heart following myocardial ischaemia which method comprises administration of an effective, non-toxic amount of a glucose uptake enhancer to a human or non-human mammal in need thereof
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(2008/06/13)
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