cas 25808-30-4, Methylaminoacetonitrile hydrochloride

Benzenesulfonamides of formula (I), in which W is OR1, NR2OR1, NRARB, NR2NRARB, or NR2(CH2)2-4NRARBand the other variables as defined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer, stroke, heart failure, xenograft rejection, arthritis, cystic fibrosis, hepatomegaly, cardiomegaly, Alzheimer's disease, complications of diabetes, septic shock, and viral infection.

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25808-30-4

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Chemical Properties

Appearance/Colour :Orange crystalline powder.

Melting Point: 103-106 °C(lit.)

Boiling Point: 150.2ºC at 760 mmHg

Flash Point:44.6ºC

Storage Temp.:Inert atmosphere,Room Temperature

Vapor Pressure: 3.89mmHg at 25°C

BRN: 3908975

PSA: 35.82000

LogP: 0.92228

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