25954-44-3

Basic information

• Product Name: GENTIANOSE
• Synonyms: GENTIANOSE;O-beta-D-glucopyranosyl-(1->6)-beta-D-fructofuranosyl-alpha-D-glucopyranoside;β-D-Fructofuranosyl 6-O-(β-D-glucopyranosyl)-α-D-glucopyranoside
• CAS NO: 25954-44-3
• Molecular Formula: C₁₈H₃₂O₁₆
• Molecular Weight: 504.44
• EINECS: 247-364-9
• Product Categories: Sugars, Carbohydrates & Glucosides
• Mol File: 25954-44-3.mol

Chemical Properties

• Melting Point: 208-210°C
• Boiling Point: 884.8oC at 760 mmHg
• Flash Point: 488.9oC
• Appearance: /
• Density: 1.81g/cm3
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Water (Slightly, Heated)
• PKA: 12.81±0.70(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: GENTIANOSE(CAS DataBase Reference)
• NIST Chemistry Reference: GENTIANOSE(25954-44-3)
• EPA Substance Registry System: GENTIANOSE(25954-44-3)

Safety Data

• Hazardous Substances Data: 25954-44-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
GENTIANOSE is used as an active ingredient for its antimicrobial, anti-inflammatory, and antioxidant properties, which can contribute to the development of new drugs and treatments for various health conditions.
Used in Cosmetics Industry:
GENTIANOSE is used as a key component in cosmetic products for its anti-inflammatory and antioxidant properties, which can help in reducing skin inflammation and promoting skin health.
Used in Food and Beverage Industry:
GENTIANOSE is used as a natural additive in the food and beverage industry for its antimicrobial properties, which can help in preserving the freshness and quality of the products.
Used in Agricultural Industry:
GENTIANOSE is used as a natural antimicrobial agent in the agricultural industry to protect crops from diseases and pests, promoting a more sustainable and eco-friendly approach to farming.

Upstream product

• 10257-28-0 D-Galactose 
• 57-50-1 Sucrose 
• 14227-87-3 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl chloride 
• 9005-25-8 starch 

Relevant articles and documents

Transglucosylation activities of multiple forms of alpha-glucosidase from spinach.

Transglucosylation activities of spinach alpha-glucosidase I and IV, which have different substrate specificity for hydrolyzing activity, were investigated. In a maltose mixture, alpha-glucosidase I, which has high activity toward not only maltooligosaccharides but also soluble starch and can hydrolyze isomaltose, produced maltotriose, isomaltose, and panose, and alpha-glucosidase IV, which has high activity toward maltooligosaccharides but faint activity toward soluble starch and isomaltose, produced maltotriose, kojibiose, and 2,4-di-alpha-D-glucosyl-glucose. Transglucosylation to sucrose by alpha-glucosidase I and IV resulted in the production of theanderose and erlose, respectively, showing that spinach alpha-glucosidase I and IV are useful to synthesize the alpha-1,6-glucosylated and alpha-1,2- and 1,4-glucosylated products, respectively.

COMBINED USE OF DIPEPTIDYL PEPTIDASE IV INHIBITOR COMPOUND AND SWEETENER

The present invention provides a novel therapeutic or preventive method, a pharmaceutical composition and use thereof, that exhibit superior anti-obesity effects (body weight-reducing (losing) effects and/or body fat mass-reducing effects). Specifically, the present invention provides a pharmaceutical composition comprising the combination of a dipeptidyl peptidase 4 inhibitor and a sweetener having a GLP-1 secretion-stimulating action, as well as use thereof for the manufacture of a medicament. The present invention also provides a method for treating or preventing obesity, comprising administering an effective amount of (a) a dipeptidyl peptidase 4 inhibitor and (b) a sweetener having a GLP-1 secretion-stimulating action to a patient suffering from symptoms of obesity.

First direct glycosylation of unprotected nonreducing mono- and disaccharides

The first single-step random-glycosylation methodology for fully unprotected glycosyl acceptors is reported by random glycosylation leading to all possible regioisomers. For such systems conventional glycosylation methods such as Koenigs-Knorr glycosylation, Schmidt's trichloroacetimidate glycosylation and reactions employing glycosyl fluoride donors fail entirely. Starting from unprotected nonreducing saccharides, the glycosylation of β-glucosylated and β-galactosylated monosaccharides (Glc, Gal), symmetric disaccharides (e.g. α,α-trehaloses) as well as unsymmetric disaccharides (e.g. sucrose) were studied. The influence of base type and concentration were examined. Several libraries of di- and trisaccharides were generated. All regioisomers were formed in approximately equal proportions, and their partial separation was achieved by flash column chromatography. Even though it appears that overall yields are lower when comparing to classical protecting-group chemistry, this synthetic effort may be superior especially for access to higher saccharides. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

REGIOSELECTIVE SYNTHESIS OF TRISACCHARIDES BY USE OF A REVERSED HYDROLYSIS ACTIVITY OF α- AND β-D-GALACTOSIDASE

Incubation of a solution containing D-galactose and a high concentration of sucrose in the presence of α-D-galactosidase from M. vinacea afforded raffinose and planteose in a ratio of ca. 3:2.On the other hand, circulation of a solution of D-galactose and sucrose through a reaction system consisting of columns, in series, of immobilized α-D-galactosidase and activated carbon gave only raffinose, eluted from the activated carbon column in a 17.6percent yield.Similarly, only isoraffinose was obtained in 10.6percent yield by the continuous method using an immobilized column of β-D-galactosidase from E. coli.