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Methyl 2-(2-amino-5-methyl-4-thiazolyl)acetate is a chemical compound characterized by its molecular formula C8H11N3O2S. It is a thiazole derivative featuring a methyl group, an amino group, and an acetate group attached to the thiazole ring. Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate has garnered interest for its potential pharmacological properties, particularly as an inhibitor of protein synthesis. Its unique structure and possible biological activities make it a valuable chemical for research and development within the pharmaceutical industry.

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  • 259654-73-4 Structure
  • Basic information

    1. Product Name: Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate
    2. Synonyms: Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate
    3. CAS NO:259654-73-4
    4. Molecular Formula: C7H10N2O2S
    5. Molecular Weight: 186.2315
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 259654-73-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 324.2±27.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.297±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 4.21±0.10(Predicted)
    10. CAS DataBase Reference: Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate(CAS DataBase Reference)
    11. NIST Chemistry Reference: Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate(259654-73-4)
    12. EPA Substance Registry System: Methyl 2-(2-AMino-5-Methyl-4-thiazolyl)acetate(259654-73-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 259654-73-4(Hazardous Substances Data)

259654-73-4 Usage

Uses

Used in Pharmaceutical Research and Development:
Methyl 2-(2-amino-5-methyl-4-thiazolyl)acetate is utilized as a research chemical for the exploration of its pharmacological properties. Its role as an inhibitor of protein synthesis is of particular interest, as it may contribute to the development of new drugs targeting specific biological pathways.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Methyl 2-(2-amino-5-methyl-4-thiazolyl)acetate serves as a key intermediate or building block for the synthesis of novel compounds with potential therapeutic applications. Its unique structure allows for the creation of new drugs that could address unmet medical needs.
Used in Drug Discovery:
Methyl 2-(2-amino-5-methyl-4-thiazolyl)acetate is employed in drug discovery processes to identify and optimize lead compounds with potential therapeutic effects. Its unique chemical features make it a promising candidate for the development of innovative pharmaceuticals.
Used in Protein Synthesis Inhibition Studies:
As a compound with known inhibitory effects on protein synthesis, Methyl 2-(2-amino-5-methyl-4-thiazolyl)acetate is used in studies aimed at understanding the mechanisms of protein synthesis inhibition. This knowledge can be applied to develop targeted therapies for diseases where protein synthesis plays a critical role.

Check Digit Verification of cas no

The CAS Registry Mumber 259654-73-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,6,5 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 259654-73:
(8*2)+(7*5)+(6*9)+(5*6)+(4*5)+(3*4)+(2*7)+(1*3)=184
184 % 10 = 4
So 259654-73-4 is a valid CAS Registry Number.

259654-73-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate

1.2 Other means of identification

Product number -
Other names (2-amino-5-methyl-thiazol-4-yl)-acetic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:259654-73-4 SDS

259654-73-4Relevant articles and documents

METHODS OF TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES BASED ON APOE4 GENOTYPE

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Paragraph 0548; 0549, (2018/06/15)

The present invention provides indane acetic acid and their derivatives and methods for the treating and/or preventing of cognitive disorders based on the ApoE4 genotype of human subjects.

METHODS OF DOSE ADMINISTRATION FOR TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES

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Paragraph 0550; 0551, (2018/06/15)

The present invention provides indane acetic acid and their derivatives and methods for the treating and/or preventing of cognitive disorders.

INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS

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Page 90, (2010/02/06)

This invention relates to novel indane, dihydrobenzofuran, and tetrahydronaphthalene carboxylic acid derivatives whice are useful in the treatment of diseases such sa diabetes, diabetes-related disorders, obesity, hyperlipidemia, and cardiovascular diseases. The invention also relates to intermediates useful in preparation of said carboxylic derivatives and to methods of preparation.

Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation

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, (2008/06/13)

This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.

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