259870-74-1

Basic information

• Product Name: Hydrazinecarboxylic acid, 1-cyclopentyl-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Hydrazinecarboxylic acid, 1-cyclopentyl-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 259870-74-1
• Molecular Formula: C10H20N2O2
• Molecular Weight: 200.278
• Product Categories: CYCLOPENTANE
• Mol File: 259870-74-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Hydrazinecarboxylic acid, 1-cyclopentyl-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarboxylic acid, 1-cyclopentyl-, 1,1-dimethylethyl ester (9CI)(259870-74-1)
• EPA Substance Registry System: Hydrazinecarboxylic acid, 1-cyclopentyl-, 1,1-dimethylethyl ester (9CI)(259870-74-1)

Safety Data

• Hazardous Substances Data: 259870-74-1(Hazardous Substances Data)

Upstream product

• 287729-05-9 N-cyclopentyl-N-tert-butyloxycarbonylaminophthalimide 
• 34387-89-8 N-(tert-butoxycarbonylamino)phthalimide 
• 870-46-2 t-butoxycarbonylhydrazine 
• 96-41-3 Cyclopentanol 
• 109473-36-1 N-tert-butyloxycarbonylaminoisophthalimide 
• 215655-64-4 1-tert-butyloxycarbonyl-2-(2'-carboxybenzoyl)-hydrazine 
• 220294-77-9 N^β,N^β-[bis(tert-butoxycarbonyl)amino]phthalimide 
• 1240041-55-7 2-benzyl 1-tert-butyl 1-cyclopentylhydrazine-1,2-dicarboxylate 

Downstream Products

• 1240041-34-2 tert-butyl 1-cyclopentyl-2-(5,5-dimethyl-3-oxocyclohex-1-enyl)-hydrazinecarboxylate 
• 24214-72-0 cyclopentylhydrazine hydrochloride 

Relevant articles and documents

Orthogonal regioselective synthesis of N-alkyl-3-substituted tetrahydroindazolones

A divergent strategy for the regioselective and orthogonal synthesis of complementary regioisomers of N-alkyl-3-substituted-tetrahydroindazolones 3 and 4 was achieved from. Boc-protected alkylhydrazmes 1. The robustness and sub-strate generality of this method were validated by synthesizing 3 and. 4 through the intra- and intermolecular condensation of 1 with various 2-acylcyclohexane-l,3-diones 2 and aldehydes, respectively.

N-tert-butoxycarbonylaminophthalimide, a versatile reagent for the conversion of alcohols into alkylated tert-butylcarbazates or hydrazines via the Mitsunobu protocol

An efficient two-step method has been developed for the conversion of alcohols to substituted hydrazines. The use of N-tert- butoxycarbonylaminophthalimide as an acid partner in Mitsunobu reactions with a variety of alcohols permits the synthesis of the corresponding monoalkylated tert-butylcarbazates and hydrazines.

New Synthesis of 1,1-Substituted Hydrazines by Alkylation of N-Acyl- or N-alkyloxycarbonylaminophthalimide Using the Mitsunobu Protocol

N-acyl- and N-alkoxycarbonylaminophthalimides are prepared using a convenient reaction and are efficiently used as acid partners in Mitsunobu reaction. This reaction allows them to be alkylated by primary, secondary or benzyl groups. Comparison of the reactivities and pKa values of these N-substituted aminophthalimides suggest that the success of the Mitsunobu reaction in this case seems to be governed more by steric than by electronic effects. A final dephthaloylation step results in an efficient method for the preparation of 1,1-substituted hydrazines.