261503-40-6 Usage
Uses
Used in Scientific Research:
3H,3H-PERFLUOROOCTANE-2,4-DIONE is used as a research tool for studying the enzyme aconitase and the citric acid cycle. Its ability to inhibit aconitase activity allows researchers to investigate the role of this enzyme in cellular metabolism and its potential as a target for therapeutic interventions.
Used in Cancer Research:
In the field of cancer research, 3H,3H-PERFLUOROOCTANE-2,4-DIONE has been explored for its potential use in medical treatments. The inhibition of aconitase by this compound can disrupt the citric acid cycle, which is essential for the energy production and growth of cancer cells. By targeting aconitase, Fluorocitrate may have the potential to inhibit tumor growth and proliferation, offering a novel approach to cancer therapy.
Used in Drug Development:
3H,3H-PERFLUOROOCTANE-2,4-DIONE can be utilized in the development of drugs targeting aconitase or the citric acid cycle. By understanding the mechanism of action of this compound, researchers can design and synthesize new molecules with improved potency, selectivity, and reduced side effects. These drugs could potentially be used in the treatment of various diseases, including cancer, by targeting the metabolic pathways essential for disease progression.
Used in Metabolic Studies:
Fluorocitrate can also be employed in metabolic studies to investigate the role of the citric acid cycle in different physiological and pathological conditions. By inhibiting aconitase, researchers can gain insights into the interplay between cellular metabolism and various biological processes, such as cell growth, differentiation, and apoptosis.
Check Digit Verification of cas no
The CAS Registry Mumber 261503-40-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,1,5,0 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 261503-40:
(8*2)+(7*6)+(6*1)+(5*5)+(4*0)+(3*3)+(2*4)+(1*0)=106
106 % 10 = 6
So 261503-40-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H2F12O2/c9-4(10,2(21)1-3(22)5(11,12)13)6(14,15)7(16,17)8(18,19)20/h1H2
261503-40-6Relevant articles and documents
New efficient synthetic routes to trifluoromethyl substituted pyrazoles and corresponding β-diketones
Grünebaum, Mariano,Buchheit, Annika,Günther, Christina,Wiemh?fer, Hans-D.
supporting information, p. 1555 - 1559 (2018/03/29)
An improved and more efficient synthesis procedure for trifluoromethyl substituted pyrazoles, namely 3,5-bis(trifluoromethyl)-1H-pyrazole (1a), 5-(pentafluoroethyl)-3-(trifluoromethyl)-1H-pyrazole (1b), 5-(heptafluoropropyl)-3-(trifluoromethyl)-1H-pyrazol
