261715-39-3

Basic information

• Product Name: 6-(1-PYRROLIDINYL)NICOTINALDEHYDE
• Synonyms: 6-(1-PYRROLIDINYL)NICOTINALDEHYDE;6-PYRROLIDIN-1-YLNICOTINALDEHYDE;6-PYRROLIDIN-1-YL-PYRIDINE-3-CARBALDEHYDE;6-(PYRROLIDIN-1-YL)PYRIDINE-3-CARBOXALDEHYDE;6-(1-Pyrrolidinyl)nicotinealdehyde;6-(1-Pyrrolidinyl)nicotinaldehyde ,97%;6-(1-Pyrrolidinyl)pyridine-3-carboxaldehyde;2-(Pyrrolidin-1-yl)pyridine-5-carboxaldehyde
• CAS NO: 261715-39-3
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176.22
• Mol File: 261715-39-3.mol

Chemical Properties

• Melting Point: 89 °C
• Boiling Point: 358.146 °C at 760 mmHg
• Flash Point: 170.401 °C
• Appearance: /
• Density: 1.184 g/cm³
• Vapor Pressure: 2.6E-05mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.26±0.29(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 6-(1-PYRROLIDINYL)NICOTINALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(1-PYRROLIDINYL)NICOTINALDEHYDE(261715-39-3)
• EPA Substance Registry System: 6-(1-PYRROLIDINYL)NICOTINALDEHYDE(261715-39-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-37
• RIDADR: 2811
• Hazardous Substances Data: 261715-39-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-(1-PYRROLIDINYL)NICOTINALDEHYDE is used as a reagent for the preparation of benzimidazole derivatives, which are potential inhibitors for the abnormal proliferation of prostatic interstitial cells. This application is particularly relevant in the treatment of prostatic hypertrophy, a condition characterized by the enlargement of the prostate gland, leading to urinary problems and other complications.
The compound's role in the pharmaceutical industry is crucial, as it aids in the development of new drugs that can help manage and treat prostatic hypertrophy more effectively. By inhibiting the abnormal cell proliferation, the benzimidazole derivatives synthesized using 6-(1-PYRROLIDINYL)NICOTINALDEHYDE can potentially alleviate the symptoms and improve the quality of life for patients suffering from this condition.

InChI:InChI=1/C10H12N2O/c13-8-9-3-4-10(11-7-9)12-5-1-2-6-12/h3-4,7-8H,1-2,5-6H2

Upstream product

• 123-75-1 pyrrolidine 
• 23100-12-1 6-chloronicotinylaldehyde 

Relevant articles and documents

Novel mesoionic compound and synthesis and application thereof

The invention discloses a novel mesoionic compound and synthesis and application thereof, and particularly discloses a novel mesoionic compound as shown in a formula (I), wherein X is CH or N. A Is phenyl. Naphthyl, 1,3 -benzodiazole -5 - base and C1

COMPOUNDS AS MODULATORS OF TLR2 SIGNALING

The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.