- Cyclic Acyl Disulfides and Acyl Selenylsulfides as the Precursors for Persulfides (RSSH), Selenylsulfides (RSeSH), and Hydrogen Sulfide (H2S)
-
The reactions of three model compounds (1-3) for cyclic acyl disulfides and cyclic acyl selenylsulfides are studied. These compounds were found to be effective precursors for persulfides (RSSH) and selenylsulfides (RSeSH) upon reacting with nucleophilic s
- Kang, Jianming,Ferrell, Aaron J.,Chen, Wei,Wang, Difei,Xian, Ming
-
-
Read Online
- Crucial role of selenium in the virucidal activity of benzisoselenazol- 3(2h)-ones and related diselenides
-
Various N-substituted benzisoselenazol-3(2H)-ones and their non-seleniumcontaining analogues have been synthesized and tested against selected viruses (HHV-1, EMCV and VSV) to determine the extent to which selenium plays a role in antiviral activity. The data presented here show that the presence of selenium is crucial for the antiviral properties of benzisoselenazol-3(2H)-ones since their isostructural analogues having different groups but lacking selenium either did not show any antiviral activity or their activity was substantially lower. The open-chain analogues of benzisoselenazol- 3(2H)-ones-diselenides also exhibited high antiviral activity while selenides and disulfides were completely inactive towards model viruses.
- Pietka-Ottlik, Magdalena,Potaczek, Piotr,Piasecki, Egbert,Mlochowski, Jacek
-
p. 8214 - 8228
(2011/03/19)
-
- A practical synthesis of N-substituted 1,2-benzisothiazolin-3-ones from N,N′-disubstituted 2,2′-dithiodibenzamides
-
A variety of N-substituted 1,2-benzisothiazolin-3-ones were easily synthesized from N,N′-disubstituted 2,2′-dithiodibenzamides in the presence of O-methylhydroxylamine hydrochloride. Derivatives with a primary, secondary, or tertiary alkyl group or an aryl group on the N-1 nitrogen of the 1,2-benzisothiazolin-3-one were obtained.
- Sano, Tomohumi,Takagi, Toshiyuki,Gama, Yasuo,Shibuya, Isao,Shimizu, Masao
-
p. 1585 - 1588
(2007/10/03)
-
- Preparation and properties of 3,1-benzoxathian-4-one derivatives
-
A simple preparation of 3,1-benzoxathian-4-one derivatives (3) from thiosalicylic acid and aldehydes, methyl and cyclic ketones, as well as 2,2-dimethoxypropane was developed. The reactivity of 3 under nucleophilic, acidic, reductive and oxidative conditions was examined.
- Siedlecka,Skarzewski
-
p. 1369 - 1374
(2007/10/03)
-
- Antithrombotic agent
-
Certain 2,2'-dithiobis-N-substituted or unsubstituted benzamides or derivatives thereof are useful as antithrombotic agents because of their ability to suppress aggregation of blood platelets.
- -
-
-
