2620-88-4Relevant academic research and scientific papers
Cyclic Acyl Disulfides and Acyl Selenylsulfides as the Precursors for Persulfides (RSSH), Selenylsulfides (RSeSH), and Hydrogen Sulfide (H2S)
Kang, Jianming,Ferrell, Aaron J.,Chen, Wei,Wang, Difei,Xian, Ming
, p. 852 - 855 (2018)
The reactions of three model compounds (1-3) for cyclic acyl disulfides and cyclic acyl selenylsulfides are studied. These compounds were found to be effective precursors for persulfides (RSSH) and selenylsulfides (RSeSH) upon reacting with nucleophilic s
Crucial role of selenium in the virucidal activity of benzisoselenazol- 3(2h)-ones and related diselenides
Pietka-Ottlik, Magdalena,Potaczek, Piotr,Piasecki, Egbert,Mlochowski, Jacek
experimental part, p. 8214 - 8228 (2011/03/19)
Various N-substituted benzisoselenazol-3(2H)-ones and their non-seleniumcontaining analogues have been synthesized and tested against selected viruses (HHV-1, EMCV and VSV) to determine the extent to which selenium plays a role in antiviral activity. The data presented here show that the presence of selenium is crucial for the antiviral properties of benzisoselenazol-3(2H)-ones since their isostructural analogues having different groups but lacking selenium either did not show any antiviral activity or their activity was substantially lower. The open-chain analogues of benzisoselenazol- 3(2H)-ones-diselenides also exhibited high antiviral activity while selenides and disulfides were completely inactive towards model viruses.
A practical synthesis of N-substituted 1,2-benzisothiazolin-3-ones from N,N′-disubstituted 2,2′-dithiodibenzamides
Sano, Tomohumi,Takagi, Toshiyuki,Gama, Yasuo,Shibuya, Isao,Shimizu, Masao
, p. 1585 - 1588 (2007/10/03)
A variety of N-substituted 1,2-benzisothiazolin-3-ones were easily synthesized from N,N′-disubstituted 2,2′-dithiodibenzamides in the presence of O-methylhydroxylamine hydrochloride. Derivatives with a primary, secondary, or tertiary alkyl group or an aryl group on the N-1 nitrogen of the 1,2-benzisothiazolin-3-one were obtained.
Preparation and properties of 3,1-benzoxathian-4-one derivatives
Siedlecka,Skarzewski
, p. 1369 - 1374 (2007/10/03)
A simple preparation of 3,1-benzoxathian-4-one derivatives (3) from thiosalicylic acid and aldehydes, methyl and cyclic ketones, as well as 2,2-dimethoxypropane was developed. The reactivity of 3 under nucleophilic, acidic, reductive and oxidative conditions was examined.
Antithrombotic agent
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, (2008/06/13)
Certain 2,2'-dithiobis-N-substituted or unsubstituted benzamides or derivatives thereof are useful as antithrombotic agents because of their ability to suppress aggregation of blood platelets.
