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3-Pyridinemethanamine,6-methoxy-(9CI), also known as 5-(Aminomethyl)-2-methoxypyridine, is an organic compound with a pyridine ring structure and a methoxy group attached to the 6th position. It features an amine group attached to the 3rd position, which contributes to its chemical reactivity and potential applications in various fields.

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  • 262295-96-5 Structure
  • Basic information

    1. Product Name: 3-Pyridinemethanamine,6-methoxy-(9CI)
    2. Synonyms: 3-Pyridinemethanamine,6-methoxy-(9CI);5-(AMinoMethyl)-2-Methoxypyridine;6-Methoxy-3-PyridineMethanaMine;3-PyridineMethanaMine, 6-Methoxy-;(6-Methoxypyridin-3-yl)methylamine, 6-Methoxynicotinylamine;5-AMinoMethyl-2-Methoxypyridine hydrochloride;3-Aminomethyl-6-methoxypyridine;6-Methoxypyridine-3-methanamine
    3. CAS NO:262295-96-5
    4. Molecular Formula: C7H10N2O
    5. Molecular Weight: 138.169
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 262295-96-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 239.342ºC at 760 mmHg
    3. Flash Point: 98.551ºC
    4. Appearance: /
    5. Density: 1.091g/cm3
    6. Vapor Pressure: 0.04mmHg at 25°C
    7. Refractive Index: 1.536
    8. Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
    9. Solubility: N/A
    10. PKA: 7.94±0.29(Predicted)
    11. CAS DataBase Reference: 3-Pyridinemethanamine,6-methoxy-(9CI)(CAS DataBase Reference)
    12. NIST Chemistry Reference: 3-Pyridinemethanamine,6-methoxy-(9CI)(262295-96-5)
    13. EPA Substance Registry System: 3-Pyridinemethanamine,6-methoxy-(9CI)(262295-96-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: 3265
    5. WGK Germany:
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup:
    9. Hazardous Substances Data: 262295-96-5(Hazardous Substances Data)

262295-96-5 Usage

Uses

Used in Organic Synthesis:
3-Pyridinemethanamine,6-methoxy-(9CI) is used as a research chemical for organic synthesis. Its unique structure allows it to be a versatile building block in the creation of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Processes:
In addition to its role in organic synthesis, 3-Pyridinemethanamine,6-methoxy-(9CI) is also utilized in other chemical processes. Its reactivity and functional groups make it suitable for use as an intermediate or catalyst in various chemical reactions, contributing to the development of new materials and products.

Check Digit Verification of cas no

The CAS Registry Mumber 262295-96-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,2,2,9 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 262295-96:
(8*2)+(7*6)+(6*2)+(5*2)+(4*9)+(3*5)+(2*9)+(1*6)=155
155 % 10 = 5
So 262295-96-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O/c1-10-7-3-2-6(4-8)5-9-7/h2-3,5H,4,8H2,1H3

262295-96-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (6-methoxypyridin-3-yl)methanamine

1.2 Other means of identification

Product number -
Other names C-(6-methoxy-[3]pyridyl)-methylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:262295-96-5 SDS

262295-96-5Relevant articles and documents

Selective catalytic transfer hydrogenation of nitriles to primary amines using Pd/C

Vilches-Herrera, Marcelo,Werkmeister, Svenja,Junge, Kathrin,Boerner, Armin,Beller, Matthias

, p. 629 - 632 (2014/03/21)

The catalytic transfer hydrogenation of (hetero)aryl nitriles using ammonium formate has been investigated in detail. In the presence of commercially available Pd/C, a straightforward and selective reduction is achieved without any additives under mild conditions.

AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS

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Page/Page column 47-48, (2012/06/01)

A method of enhancing binding of cells to an integrin-binding ligand comprises treating integrin-expressing cells in vitro with an agonist of integrin, wherein the integrin is selected from the group consisting of α4β1, α5β1, α4β7, αvβ3 and αLβ2, and contacting the treated cells with an integrin-binding ligand; integrin agonist compounds having the general formula I; methods of treating integrin-expressing cells with such agonists to enhance binding; and therapeutic methods comprising administering agonist-treated cells or agonist compounds to a mammal.

One-pot primary aminomethylation of aryl and heteroaryl halides with sodium phthalimidomethyltrifluoroborate

Murai, Norio,Miyano, Masayuki,Yonaga, Masahiro,Tanaka, Keigo

supporting information; experimental part, p. 2818 - 2821 (2012/07/17)

A one-pot primary aminomethylation of aryl halides, triflates, mesylates, and tosylates via Suzuki-Miyaura cross-coupling reactions with sodium phthalimidomethyltrifluoroborate followed by deamidation with ethylenediamine is reported.

Ruthenium N-heterocyclic carbene catalysts for selective reduction of nitriles to primary amines

Addis, Daniele,Enthaler, Stephan,Junge, Kathrin,Wendt, Bianca,Beller, Matthias

experimental part, p. 3654 - 3656 (2009/10/04)

Easily accessible in situ catalysts composed of [Ru(cod)(2-methylallyl)2] and N-heterocyclic carbene ligands have been developed for the environmentally benign hydrogenation of various nitriles to give primary amines. Applying optimized conditions in the presence of SIMesBF4 as ligand high catalyst activity of up to 392 h-1 is achieved in the hydrogenation of benzonitrile. The general applicability and functional group tolerance of this novel catalyst system are shown in the reduction of ten different nitriles.

A general and environmentally benign catalytic reduction of nitriles to primary amines

Enthaler, Stephan,Addis, Daniele,Junge, Kathrin,Erre, Giulia,Beller, Matthias

experimental part, p. 9491 - 9494 (2009/10/14)

An easily accessible in situ catalyst composed of [Ru(cod)methylallyl 2] and DPPF was developed for the environmentally benign hydrogenation of various nitriles to give primary amines. A solution of benzonitrile in toluene was transferred by syringe into an autoclave that contained argon and KOtBu. The catalyst was generated in situ by stirring [Ru(cod)methylallyl2] and DPPF in toluene for 10 min and transferring the solution by syringe into the autoclave. the reaction mixture was filtered through a short plug of silica gel and the yield was measured by GC. A superior catalyst activity with a TOF of up to 5783 h-1 is achieved in the model reaction under optimized conditions. The results also show that [Ru(cod)methylallyl2]/DPPF catalyst system exhibit a broad functional group tolerance.

7-Substituted Purine Derivatives for Immunosuppression

-

Page/Page column 10, (2008/12/05)

The present invention provides novel purinone and related derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formula III:

Cyanophenyl derivative

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Page column 18, (2010/11/30)

This application relates to a piperazino-substituted novel cyanophenyl derivative in which a substituted carbamoyl or substituted sulfamoyl group having an aryl, heterocyclic or the like group that may have a substituent group is bonded to one nitrogen atom on the piperazine ring. The compound of this application has an anti-androgen action and is useful in preventing or treating prostatic cancer, benign prostatic hyperplasia and the like diseases.

Synthesis and herbicidal activity of 2-cyano-3-substituted-pyridinemethylaminoacrylates

Wang, Qingmin,Sun, Huikai,Cao, Huanyan,Cheng, Muru,Huang, Runqiu

, p. 5030 - 5035 (2007/10/03)

Two series of 2-cyano-3-substituted-pyridinemethylaminoacrylates, namely 12 new (Z)-2-cyano-3-methylthio-3-substituted-pyridinemethaneaminoacrylates and 10 new (Z)-2-cyano-3-alkyl-3-substituted-pyridinemethaneaminoacrylates, were synthesized as herbicidal inhibitors of photosystem II (PSII) electron transport. All of these compounds were confirmed by 1H NMR, elemental, IR, and mass spectrum analyses. Their herbicidal activities were evaluated. Some compounds exhibited excellent herbicidal activities, even at a dose of 75 g/ha. A suitable substituent at the 2-position of the pyridine ring and the well-fit group at the 3-position of acrylate were essential for high herbicidal activity. 2-Cyanoacrylates containing a substituted pyridine ring provide higher herbicidal activities than parent compounds containing phenyl. These PSII inhibitor herbicides are safe to corn, which is a major crop in China.

CYANOPHENYL DERIVATIVES

-

, (2008/06/13)

This application relates to a piperazino-substituted novel cyanophenyl derivative in which a substituted carbamoyl or substituted sulfamoyl group having an aryl, heterocyclic or the like group that may have a substituent group is bonded to one nitrogen atom on the piperazine ring. The compound of this application has an anti-androgen action and is useful in preventing or treating prostatic cancer, benign prostatic hyperplasia and the like diseases.

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