2623-45-2

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 2-chloro-1-(2,4-dimethylphenyl)(9CI) is used as an intermediate in the production of pharmaceuticals for its ability to react with a variety of reagents, making it a versatile building block in organic synthesis.
Used in Agrochemical Industry:
Ethanone, 2-chloro-1-(2,4-dimethylphenyl)(9CI) is used in the manufacturing of agrochemicals, contributing to the development of various specialty chemicals.
Used in Fine Chemicals Industry:
Ethanone, 2-chloro-1-(2,4-dimethylphenyl)(9CI) is used as an intermediate in the production of fine chemicals due to its reactivity and versatility in organic synthesis.
It is important to handle Ethanone, 2-chloro-1-(2,4-dimethylphenyl)(9CI) with care as it is flammable and may cause irritation to the skin, eyes, and respiratory system if not handled properly.

InChI:InChI=1/C10H11ClO/c1-7-3-4-9(8(2)5-7)10(12)6-11/h3-5H,6H2,1-2H3

Upstream product

• 854861-66-8 1-iodoethynyl-2,4-dimethyl-benzene 
• 182115-37-3 2-oxo-2H-chromen-7-yl chloroethanoate 
• 108-38-3 m-xylene 
• 105738-24-7 7-chloroacetyloxy-4-methylcoumarin 
• 64-17-5 ethanol 
• 79-11-8 chloroacetic acid 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 109646-60-8 1-(2,4-dimethyl-phenacyl)-3-hydroxy-pyridinium; chloride 
• 842136-27-0 5-bromo-2,4-dimethylbenzoic acid 
• 65143-39-7 2-(2,4-dimethylphenyl)-2-oxoethyl acetate 
• 554-68-7 triethylamine hydrochloride 
• 120027-77-2 3-[2-(2,4-Dimethyl-phenyl)-2-oxo-ethyl]-3H-benzooxazol-2-one 
• 120007-61-6 2-(Benzooxazol-2-ylsulfanyl)-1-(2,4-dimethyl-phenyl)-ethanone 
• 611-01-8 2,4-dimethyl-benzoic acid 

Relevant academic research and scientific papers

Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin

A series of α-triazolyl chalcones were efficiently synthesized. Most of the prepared compounds showed effective antibacterial and antifungal activities. Noticeably, α-triazolyl derivative 9a exhibited low MIC value of 4 μg/mL against MRSA and Micrococcus luteus, which was comparable or even superior to reference drugs. The further research revealed that compound 9a could effectively intercalate into Calf Thymus DNA to form 9a-DNA complex which might block DNA replication to exert their powerful antimicrobial activities. Competitive interactions between 9a and metal ions to Human Serum Albumin (HSA) suggested the participation of Fe3+, K+ and Mg 2+ ions in 9a-HSA system could increase the concentration of free 9a, shorten its storage time and half-life in the blood, thus improving its antimicrobial efficacy.

The colored curable composition, and its manufacturing method, a color filter, a liquid crystal display device, a solid-state imaging device, and, a dye compd.

Provided is a curable colored composition, transmitting the light in the magenta region and absorbing the light in the cyan region. A curable colored composition comprising a metal complex in which a compound represented by formula (I) below is coordinated to a metal atom or a metal compound.

Simple and efficient procedure for the friedel-crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/AL2O3 under heterogeneous conditions

An efficient and chemoselective method for the Friedel-Crafts acylation of aromatic compounds using P2O5/Al2O3 and carboxylic acids. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones in good yields.

Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 under heterogeneous conditions

A convenient and efficient procedure for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of P2O5/SiO2 is described. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones. The use of non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.

Chloroacetylation of arenes using chloroacetyl chloride in the presence of FeCl3 modified montmorillonite K10

Chloroacetylation reaction of arenes using chloroacetyl chloride has been studied in the presence of Fe-modified montmorillonite K10 catalysts in a liquid phase. The catalysts have been prepared by treating montmorillonite K10 with aqueous solution of FeCl3. Good yields and selectivity are observed for the acylated product.

ZnI2/NaCNBH3 as an Efficient Reagent for Regioselective Ring Opening of the Benzylic Epoxide Moiety

In the presence of zinc iodide, sodium cyanoborohydride was found to produce regioselective ring opening of benzylic epoxides in mild reaction conditions.

Intermolecular character of the Fris rearrangement in the series of acyloxycoumarins

In the study of the Fris rearrangement in the series of 7-and 4-acyloxycoumarins we obtained certain data indicating intermolecular character of the rearrangement. The Fris rearrangement of a mixture of 7-benzoyloxy-4-metylcoumarin and 7-acetoxycoumarin results in formation of four reaction products in approximately equal molar ratio. Also, four products were obtained in the Fris rearrangement of 7-and 4-acyloxycoumarins in the presence of hydroxycoumarins. The Fris rearrangement of acyloxycoumarins in the presence of m-xylene at acylcoumarin-m-xylene ratio of 1:6 leads to the corresponding hydroxycoumarins and acylated m-xylenes. Intermediate formation of acylium ions was also detected by evolution of carbon monooxide at the Fris rearrangement of 7-pyvaloyloxy-and 7-isobutyryloxy-4-methylcoumarins. A product of intermolecular migration, 3-acetyl-4-hydoxy-6-methylcoumarin, was discovered also in the rearrangement of 4-acetoxycoumarin in the presence of 4-hydoxy-6-methylcoumarin catalyzed by phosphorus oxychloride.