263017-03-4

Basic information

• Product Name: Carbamic acid, [(1S)-1-(hydroxymethyl)-1-methyl-2-propynyl]-, 1,1-
• Synonyms: Carbamic acid, [(1S)-1-(hydroxymethyl)-1-methyl-2-propynyl]-, 1,1-
• CAS NO: 263017-03-4
• Molecular Formula: C10H17NO3
• Molecular Weight: 199.24688
• Product Categories: N-BOC
• Mol File: 263017-03-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, [(1S)-1-(hydroxymethyl)-1-methyl-2-propynyl]-, 1,1-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-1-(hydroxymethyl)-1-methyl-2-propynyl]-, 1,1-(263017-03-4)
• EPA Substance Registry System: Carbamic acid, [(1S)-1-(hydroxymethyl)-1-methyl-2-propynyl]-, 1,1-(263017-03-4)

Safety Data

• Hazardous Substances Data: 263017-03-4(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 263016-99-5 (R)-N-(tert-butoxycarbonyl)-4-(2',2'-dibromoethenyl)-2,2,4-trimethyl-3-oxazolidine 
• 34619-03-9 tert-butyldicarbonate 
• 391678-34-5 4-ethynyl-2,2,4-trimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 391678-36-7 (2S)-t-Butoxycarbonylamino-2-methyl-3-butynic Acid 

Relevant articles and documents

Amino alcohol derivatives

Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives: wherein R1 and R2 are a hydrogen atom, an amino protecting group; R3 is a hydrogen atom, a hydroxy protecting group; R4 is a lower alkyl group; n is an integer from 1 to 6; X is an ethylene group; Y is a C1-C10 alkylene group, a C1-C10 alkylene group substituted with 1 to 3 substituents selected from substituent group a and b; R5 is an aryl group; R6 and R7 are a hydrogen atom, a group selected from substituent group a; with the proviso when R5 is a hydrogen atom, Y is not a single bond or a straight chain C1-C10 alkylene group.

A straightforward synthesis of both enantiomers of α-vinylalanine and α-ethynylalanine

This report describes the synthesis of enantiomerically pure (S)- and (R)-α-vinylalanines and (S)- and (R)-α-ethynylalanines, four quaternary α- amino acids, using a straightforward synthetic route and starting from (S)- and (R)-N-Boc-N,O-isopropylidene-α-methylserinals. (C) 1999 Elsevier Science Ltd.