26747-12-6

Basic information

• Product Name: poly(9-vinyladenine)
• Synonyms: poly(9-vinyladenine)
• CAS NO: 26747-12-6
• Molecular Formula: C7H7N5
• Molecular Weight: 161.16398
• Mol File: 26747-12-6.mol

Chemical Properties

• Boiling Point: 409.6°C at 760 mmHg
• Flash Point: 201.5°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 6.4E-07mmHg at 25°C
• Refractive Index: 1.753
• CAS DataBase Reference: poly(9-vinyladenine)(CAS DataBase Reference)
• NIST Chemistry Reference: poly(9-vinyladenine)(26747-12-6)
• EPA Substance Registry System: poly(9-vinyladenine)(26747-12-6)

Safety Data

• Hazardous Substances Data: 26747-12-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H7N5/c1-2-12-4-11-5-6(8)9-3-10-7(5)12/h2-4H,1H2,(H2,8,9,10)

Upstream product

• 106-93-4 ethylene dibromide 
• 66224-66-6 adenine 
• 75-07-0 acetaldehyde 
• 15816-12-3 6-chloro-9-vinylpurine 
• 4005-49-6 N-benzoyladenine 
• 79293-84-8 N-(tert-butyldimethylsilyl)phthalimide 
• 68217-74-3 9‐(2‐bromoethyl)‐9H‐purin‐6‐amine 
• 19255-48-2 9-(2-chloroethyl)adenine 

Relevant articles and documents

Direct Prebiotic Pathway to DNA Nucleosides

It is assumed that RNA played a key role in the origin of life, and the transition to more complex but more stable DNA for continuous information storage and replication requires the development of a ribonucleotide reductase to obtain the deoxyribonucleot

UNSATURATED HETEROCYCLIC DERIVATIVES

This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

A convenient method for the synthesis of N-vinyl derivatives of nucleobases

Trimethylsilyl trifluoromethanesulfonate (TMSOTf) reveals, one more time, its enormous flexibility as Lewis acid catalyst, transforming the well known, but drastic, exchange of the acetyl group of vinyl acetate with pyrimidine and purine derivatives in a very gentle and quick method to obtain a whole set of vinyl nucleobases.

Synthesis and study of a new adenine-acridine tandem, inhibitor of exonuclease III

A new heterodimer adenine-chain-acridine containing a mixed amido-guanidinium linker chain was synthesized. To achieve the synthesis a new method of introduction of aminoalkyl chain at position 9 of adenine was designed. The heterodimer interacts specifically with the abasic sites in DNA and inhibits the major base excision repair enzyme in Escherichia coli, Exonuclease III. (C) 2000 Elsevier Science Ltd. All rights reserved.

A simple preparation of N-vinyl derivatives of DNA nucleobases

1-Vinylpyrimidines and 9-vinylpurines have been prepared via selective alkylation of the heterocyclic ring with 1,2-dibromoethane (or 1,2- dibromopropanol) followed by dehydrobromination with sodium ethoxide in ethanol/DMF.

Photochemical reactivity of 9-vinyladenine with diethyl fumarate

The photochemical reaction between 9-vinyladenine (2) and diethyl fumarate (4) gave an unusual photoadduct, epimers 4 and 5, probably derived from attack of the vinyl group on N-3 and reaction of diethyl fumarate on N-9 and N-6.