269743-56-8

Basic information

• Product Name: 2-(2-[(4-BROMOPHENYL)SULFANYL]ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
• Synonyms: 2-(2-[(4-BROMOPHENYL)SULFANYL]ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE;2-{2-[(4-bromophenyl)sulfanyl]ethyl}-2,3-dihydro-1H-isoindole-1,3-dione
• CAS NO: 269743-56-8
• Molecular Formula: C₁₆H₁₂BrNO₂S
• Molecular Weight: 362.24
• Mol File: 269743-56-8.mol

Chemical Properties

• Boiling Point: 485.9±30.0 °C(Predicted)
• Appearance: /
• Density: 1.61±0.1 g/cm3(Predicted)
• PKA: -2.26±0.20(Predicted)
• CAS DataBase Reference: 2-(2-[(4-BROMOPHENYL)SULFANYL]ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-[(4-BROMOPHENYL)SULFANYL]ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE(269743-56-8)
• EPA Substance Registry System: 2-(2-[(4-BROMOPHENYL)SULFANYL]ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE(269743-56-8)

Safety Data

• Hazardous Substances Data: 269743-56-8(Hazardous Substances Data)

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 13457-82-4 4-bromothiophenol sodium salt 
• 106-53-6 para-bromobenzenethiol 

Downstream Products

• 69326-62-1 2-(4-bromo-phenylsulfanyl)-ethylamine 

Relevant articles and documents

PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.

Synthesis, spectral studies and C-S, C-N bond fissions of some novel N-[alkyl (4′-substituted phenylthio)] phthalimides

N-[(4′-Substituted phenylthio)ethyl] phthalimide la-g and their corresponding n-propyl 2a-g, n-butyl 3a-g derivatives have been synthesised. The structure of these compounds were proved by UV, IR, 1H NMR, 13CMR and mass spectra. The 1H and 13C chemical shifts of the adjacent methylene protons and carbons of both the sulfur atom and phthalimido nitrogen group were reasonably correlated using σ° values. The carbon-nitrogen and the carbon-sulfur bond fissions in alkaline and acidic media were discussed.