27361-14-4

Basic information

• Product Name: 1-Butyl-2(1H)-pyridinone
• Synonyms: 2(1H)-Pyridone,1-butyl- (8CI); 1-Butyl-2(1H)-pyridone; 1-Butyl-2-pyridone; N-Butyl-2-pyridone
• CAS NO: 27361-14-4
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• Mol File: 27361-14-4.mol

Chemical Properties

• Boiling Point: 294.9°Cat760mmHg
• Flash Point: 135.7°C
• Appearance: /
• Density: 1g/cm³
• Vapor Pressure: 0.00157mmHg at 25°C
• Refractive Index: 1.501
• PKA: 0.31±0.20(Predicted)
• CAS DataBase Reference: 1-Butyl-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butyl-2(1H)-pyridinone(27361-14-4)
• EPA Substance Registry System: 1-Butyl-2(1H)-pyridinone(27361-14-4)

Safety Data

• Hazardous Substances Data: 27361-14-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H13NO/c1-2-3-7-10-8-5-4-6-9(10)11/h4-6,8H,2-3,7H2,1H3

Upstream product

• 142-08-5 2-Pyridone 
• 109-65-9 1-bromo-butane 
• 109-04-6 2-bromo-pyridine 
• 1628-89-3 2-methoxypyridine 
• 142-08-5 2-hydroxypyridin 
• 109-69-3 n-Butyl chloride 
• 542-69-8 1-iodo-butane 
• 778-28-9 butyl para-toluenesulfonate 
• 874-80-6 1-butylpyridinium bromide 
• 85100-77-2 1-n-butyl-3-methylimidazolim bromide 

Downstream Products

• 4789-08-6 1-Butyl 2-Piperidinone 
• 873398-00-6 1-butyl-1H-pyridine-2-thione 
• 82493-68-3 2-butyl-2-azabicyclo[2.2.0]hex-5-en-3-one 
• 82493-66-1 (1α,2β,5β,6α)-3,7-dibutyl-3,7-diazatricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 82493-66-1 (1α,2α,5α,6α)-3,7-dibutyl-3,7-diazatricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 82493-69-4 (1S,2S,5R,6R)-3,8-Dibutyl-3,8-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,7-dione 
• 82493-68-3 (1S,4R)-2-Butyl-2-aza-bicyclo[2.2.0]hex-5-en-3-one 
• 82535-45-3 (1R,2S,5R,6S)-3,8-Dibutyl-3,8-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,7-dione 
• 75608-94-5 5-methoxy-3-oxo-2-azabicyclo<2.2.0>hex-5-one 
• 13200-29-8 1-Butyl-piperidin-2-thion 

Relevant articles and documents

Microwave assisted rapid preparation of N-alkyl-2-pyridones under neutral conditions by Hilbert-Johnson reaction

The reactions of 2-methoxypyridine with haloalkanes without solvent and catalyst under microwave irradiation (100-200 °C, 5 min) yielded the corresponding N-alkyl-2(1H)-pyridones in good to moderate yields. However, the reactions were sensitive to length of haloalkanes. In contrast, the reactions of 2-alkoxypyridines with corresponding iodoalkanes under microwave irradiation (150 °C) proceeded rapidly without catalyst and solvent, and were complete within 5 min to afford N-alkyl-2(1H)-pyridones in good to excellent yields. The Japan Institute of Heterocyclic Chemistry.

Alkylation of the 2-hydroxypyridine anion in ionic liquid media

The alkylation reaction of the ambident 2-hydroxypyridine anion was examined in ionic liquid media. Ionic liquids increase the alkylation reaction rate in comparison with molecular liquids, as well as the level of impact on the reaction rates of the count

Selective alkylation of 2-pyridone in solvent-free conditions

Alkylation of 2-pyridone has been performed in solvent-free conditions. The effect of base, phase transfer agent, and alkylation agent has been discussed.