Wash the bromide with conc H2SO4, water, 10% Na2CO3 and again with H2O. Dry it over CaCl2, CaSO4 or K2CO3, and distil it. Redistil it after drying with P2O5, or pass it through two columns containing 5:1 silica gel/Celite mixture and store it with freshly activated alumina. [Beilstein 1 IV 258.]
Journal of the American Chemical Society, 86, p. 964, 1964 DOI: 10.1021/ja01059a073Organic Syntheses, Coll. Vol. 1, p. 25, 1941Synthesis, p. 326, 1982
UN1126 & UN23391- & 2-Bromobutane,
Hazard Class: 3; Labels: 3—Flammable liquid.
clear colorless to slightly yellow liquid
Flammable, dangerous fire risk.
Moderately toxic by
intraperitoneal route. Mddly toxic by
inhalation. Dangerous fire hazard when
exposed to heat, flame, or oxidizers. Violent
reaction with bromobenzene + sodium
above 30℃. Can react with oxidizing
materials. To fight fire, use CO2, dry
chemical, mist or spray. See also
1-Bromobutane is used in the synthesis of procaine and tetracaine.
1-Bromobutane is incompatible with strong bases and oxidizers [USCG, 1999].
Vapor may form explosive mixture with
air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, epoxides. May accumulate static electrical
charges and cause ignition of its vapors.
A clear colorless liquid. Flash point 65°F. Denser than water and insoluble in water. Vapors heavier than air.
Irritating to the eyes, nose, throat, and upper respiratory tract. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Irritating to the skin.
Air & Water Reactions
Highly flammable. Insoluble in water.
Butyl bromide is a highly flammable, colorless liquid with a pleasant odor. Molecular weight 5
137.04. Specific gravity (H2O:1) 5 1.28 @ 20C; boiling
point 5 101.3C; freezing/melting point 5 2112.4; vapor
pressure 5 42 mmHg @ 25C; vapor density (air 5 1) 5
4.68; flash point 5 17.2C (n-); 21C (sec-isomer).
Autoignition temperature 5 269C. Explosive limits: LEL:
2.5% @ 100C; UEL: 6.6% @ 100C. Hazard identification (based on NFPA-704 M Rating System): Health 1;
flammability 3; reactivity 0 ?. Insoluble in water
Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal,
state, and local environmental regulations must be observed