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273727-89-2

1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-, also known as methylnaphthidate, is a chemical compound that contains propanone and a substituted phenethylamine structure. It is a psychoactive drug and a research chemical that acts as a dopamine reuptake inhibitor.
Used in Pharmaceutical Industry:
1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)is used as a psychoactive drug for its stimulant properties, producing feelings of euphoria, increased energy, and alertness.
Used in Research Industry:
1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)is used as a research chemical to study its effects on the dopamine reuptake process and its potential applications in the development of new medications.
Used in Recreational Substances:
1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)is used as a designer drug, often sold online as a recreational substance. However, its safety and potential long-term effects are not well understood, and it is regulated in some jurisdictions to control its production and distribution to prevent misuse and potential harm to consumers.

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  • 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-

    Cas No: 273727-89-2

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  • 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-

    Cas No: 273727-89-2

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  • 273727-89-2 Structure

  • Basic information

    1. Product Name: 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-
    2. Synonyms: 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-
    3. CAS NO:273727-89-2
    4. Molecular Formula: C23H25NO
    5. Molecular Weight: 331.45
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 273727-89-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 478.8±28.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.083±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 7.99±0.50(Predicted)
    10. CAS DataBase Reference: 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-(273727-89-2)
    12. EPA Substance Registry System: 1-Propanone, 3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)-(273727-89-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 273727-89-2(Hazardous Substances Data)

273727-89-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 273727-89-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,3,7,2 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 273727-89:
(8*2)+(7*7)+(6*3)+(5*7)+(4*2)+(3*7)+(2*8)+(1*9)=172
172 % 10 = 2
So 273727-89-2 is a valid CAS Registry Number.

273727-89-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-naphtyl 2-(N-isopropyl-N-benzylamino)ethyl ketone

1.2 Other means of identification

Product number -
Other names 1-Propanone,3-[(1-methylethyl)(phenylmethyl)amino]-1-(2-naphthalenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:273727-89-2 SDS

273727-89-2Relevant articles and documents

Part 2. Notch-sparing γ-secretase inhibitors: The study of novel γ-amino naphthyl alcohols

Wei, Han-Xun,Lu, Dai,Sun, Vivien,Zhang, Jing,Gu, Yongli,Osenkowski, Pamela,Ye, Wenjuan,Selkoe, Dennis J.,Wolfe, Michael S.,Augelli-Szafran, Corinne E.

, p. 2133 - 2137 (2016/04/20)

One therapeutic approach for Alzheimer's disease is to inhibit the cleavage of the amyloid precursor protein (APP) by γ-secretase. At the beginning of a series of studies from our laboratories, a series of novel γ-amino alcohols (1) were found to possess γ-secretase inhibitory activity and Notch-sparing effects. A new one-pot synthesis of γ-amino alcohols and the structure-activity relationship (SAR) of these analogs will be discussed.

PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME

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Page/Page column 35, (2012/11/08)

The present invention relates to: a ketone compound having transglutaminase-inhibiting activity, which is represented by the following Formula 1, 2, or 3: wherein R1 is a substituted or unsubstituted aryl or heterocyclyl group, R2, R3, and R4 are hydrogen atoms, n is 2, X is halogen, R5 and R6 independently represent a hydrogen atom or a substituted or unsubstituted C1-C10 alkyl, aryl, or aralkyl group, wherein R5 and R6 are not hydrogen atoms at the same time, or R5 and R6 may be taken together to form a saturated or unsaturated and substituted or unsubstituted heterocyclyl group containing a nitrogen atom (N); an inhibitor of protein crosslinking comprising the compound; and a composition for preventing or treating a protein-crosslinking causative disease, which comprises the compound or the protein crosslinking inhibitor.

SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGYS AND THEREOF

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Page/Page column 39-40, (2009/05/28)

Aspects of the invention relate to substituted aryl propylamino-oxy-analogs and uses thereof. Aspects of the invention relate to compositions that are inhibitors of γ-secretase and uses thereof for treating subjects having, or at risk of developing, Alzheimer's disease.

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