6-Nitro-1-β-Naphthalenesulfonyloxybenzotriazole : A Novel Coupling Reagent For Peptide Synthesis
Synthesis of 6-nitro-1-β-naphthalenesulfonyloxybenzotriazole (N-NSBt) and its application as a peptide coupling ragent is being reported.It has been found to be suitable for rapid and quantitative synthesis of optically pure peptides in a stepwise manner.
Devadas, Balekudru,Kundu, Bijoy,Srivastava, Alka,Mathur, Krishna B.
p. 6455 - 6458
(2007/10/02)
A NOVEL ROUTE TO DIPEPTIDE AND ITS DERIVATIVE BY MEANS OF THE PALLADIUM CATALYZED FACILE CLEAVAGE OF 1-(1-METHOXYCARBONYL)ALKYL-3-SUBSTITUTED-4-ARYLAZETIDIN-2-ONES
1-(1-Methoxycarbonyl)alkyl-3-substituted-4-arylazetidin-2-ones were found to be cleaved exclusively at the N-C4 bond by the hydrogenolysis on palladium catalyst to give the corresponding dipeptide and its derivative in excellent yields.
Ojima, Iwao,Suga, Shigemi,Abe, Rumiko
p. 3907 - 3910
(2007/10/02)
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