27848-80-2

Basic information

• Product Name: L-LACTIC ACID LITHIUM SALT
• Synonyms: SARCOLACTIC ACID LITHIUM SALT;(S)-2-HYDROXYPROPIONIC ACID LITHIUM SALT;2-HYDROXYPROPIONIC ACID, LITHIUM SALT;L(+)-LACTIC ACID LITHIUM SALT;L-LACTIC ACID LITHIUM SALT;LITHIUM (S)-2-HYDROXYPROPIONATE;LITHIUM L(+)-LACTATE;LITHIUM L-LACTATE
• CAS NO: 27848-80-2
• Molecular Formula: C₃H₅O₃*Li
• Molecular Weight: 96.01
• EINECS: 248-692-5
• Product Categories: Building Blocks for Liquid Crystals;Carboxylic Acids (Chiral);Chiral Building Blocks;Chiral Compounds (Building Blocks for Liquid Crystals);Classes of Metal Compounds;Functional Materials;Li (Lithium) Compounds;Synthetic Organic Chemistry;Typical Metal Compounds
• Mol File: 27848-80-2.mol

Chemical Properties

• Melting Point: 75 °C
• Boiling Point: 200 °C
• Appearance: White/Fine Crystalline Powder
• Density: 1,325g/cm
• Refractive Index: -14 ° (C=5, H2O)
• Storage Temp.: -20°C
• Water Solubility: almost transparency in Water
• Sensitive: Hygroscopic
• BRN: 6127244
• CAS DataBase Reference: L-LACTIC ACID LITHIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: L-LACTIC ACID LITHIUM SALT(27848-80-2)
• EPA Substance Registry System: L-LACTIC ACID LITHIUM SALT(27848-80-2)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-36/37/38
• Safety Statements: 22-24/25-45-36/37/39-26
• WGK Germany: 3
• RTECS: OJ6311000
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 27848-80-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
L-Lactic Acid Lithium Salt is used as a chiral synthon for the synthesis of various pharmaceutical compounds, providing a key building block for the development of new drugs with improved efficacy and selectivity.
Used in Peptide Synthesis:
L-Lactic Acid Lithium Salt is used as a building block for the synthesis of depsipeptides, which are a class of peptides containing both amide and ester linkages. These depsipeptides have potential applications in various fields, including medicine, agriculture, and materials science, due to their unique properties and diverse biological activities.

Biochem/physiol Actions

L-lactate is produced from pyruvate by the enzyme Lacate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells.

InChI:InChI=1/C3H6O3.Li/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1

Upstream product

• 867-55-0 lithium L-lactate 

Downstream Products

• 56777-24-3 benzyl (S)-Lactate 
• 38410-64-9 p-bromophenacyl L-lactate 
• 2922-61-4 lithium hydroxypyruvate 
• 867-55-0 lithium D-lactate 
• 1301763-92-7 {[(2S)-2-hydroxypropanoyl]oxy}methyl (4S,5S)-5-[(2S)-2-(3-amino-2,2-dimethyl-3-oxopropylaminocarbonyl)-3-methylbutyl]-4-{(2S)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutyl}-1,3-oxazolidine-3-carboxylate 
• 687-47-8 (S)-Ethyl lactate 

Relevant articles and documents

Complete conversion of l-lactate into d-lactate. A generic approach involving enzymatic catalysis, electrochemical oxidation of NADH, and electrochemical reduction of pyruvate

L-Lactate was converted into D-lactate with a yield better than 97%, the system involving stereospecific catalysis of L-lactate oxidation by the rather cheap L-lactate dehydrogenase plus electrochemical regeneration of NAD+ at the anode and electrochemical reduction of pyruvate at the cathode. Such an approach can be extended to mere deracemization or complete inversion of all types of chiral α-alcohol-acids provided that the dehydrogenase related to the isomer to be inverted is available. Efficiency was not limited by enzyme or coenzyme deactivations.