- Synthesis and Properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
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The reaction of 3-pentylpentane-2,4-dione with cyanothioacetamide afforded 4,6-dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile. Alkylation of the latter led to the formation of 2-alkylsulfanyl-4,6-dimethyl-5-pentylpyridine-3-carbonitriles or 3-amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines, depending on the alkylating agent and reaction conditions. The structures of the key compounds were proved by 2D NMR spectroscopy and X-ray analysis. Biological activity of the synthesized compounds was evaluated in silico. Some compounds were experimentally found to stimulate growth of sunflower seedlings.
- Buryi,Dotsenko,Aksenov,Aksenova,Krivokolysko,Dyadyuchenko
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- High-yielding synthesis of β-octaalkyl-meso-(bromophenyl)-substituted porphyrins and X-ray study of axial complexes of their zinc complexes with THF and 1,4-dioxane
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New 5-(4-bromophenyl)-3,7,12,13,17,18-hexamethyl-2,8-dipentyl- and 5,15-bis(4-bromophenyl)-2,8,12,18-tetramethyl-2,8,12,18-tetrapentylporphyrins (H2P-1 and H2P-2) and their zinc metal complexes (ZnP-1 and ZnP-2, respectively) were sy
- Mikhalitsyna, Elena A.,Tyurin, Vladimir S.,Nefedov, Sergey E.,Syrbu, Sergey A.,Semeikin, Aleksandr S.,Koifman, Oskar I.,Beletskaya, Irina P.
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p. 5979 - 5990
(2013/02/26)
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