280116-80-5

Basic information

• Product Name: n-butyl(5-bromopyridin-2-yl)amine
• Synonyms: n-butyl(5-bromopyridin-2-yl)amine;2-Butylamino-5-bromopyridine
• CAS NO: 280116-80-5
• Molecular Formula: C9H13BrN2
• Molecular Weight: 229
• Mol File: 280116-80-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: n-butyl(5-bromopyridin-2-yl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: n-butyl(5-bromopyridin-2-yl)amine(280116-80-5)
• EPA Substance Registry System: n-butyl(5-bromopyridin-2-yl)amine(280116-80-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 280116-80-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
n-butyl(5-bromopyridin-2-yl)amine is utilized as a building block in organic synthesis for the preparation of a range of biologically active molecules. Its unique structure allows for the creation of diverse compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In pharmaceutical research, n-butyl(5-bromopyridin-2-yl)amine serves as a key intermediate for the synthesis of drugs. Its reactivity, particularly from the 5-bromopyridin-2-yl group, enables it to participate in multiple chemical reactions, facilitating the development of new pharmaceutical agents.
Used in Agrochemicals:
n-butyl(5-bromopyridin-2-yl)amine is also employed as an intermediate in the synthesis of agrochemicals. Its ability to engage in various chemical reactions makes it a valuable component in the development of agricultural products designed to improve crop yields and protect plants from pests.
Used in Specialty Chemicals:
n-butyl(5-bromopyridin-2-yl)amine finds application in the production of specialty chemicals, where its unique structure and reactivity are leveraged to create specific chemical entities for use in industries such as coatings, adhesives, and other high-value chemical markets.

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 544-16-1 n-Butyl nitrite 
• 1493-13-6 trifluorormethanesulfonic acid 
• 624-28-2 2,5-dibromopyridine 
• 109-73-9 N-butylamine 
• 157020-26-3 pyridinium N-<2'-(5'-bromopyridyl)>aminide 

Downstream Products

• 1202243-06-8 C₁₅H₁₆Cl₂N₂ 

Relevant articles and documents

A new synthesis of pyridinyl trifluoromethanesulfonates via one-pot diazotization of aminopyridines in the presence of trifluoromethanesulfonic acid

The first method for the direct one-pot transformation of aminopyridines into pyridinyl trifluoromethanesulfonates is developed. The procedure involves diazotization of aminopyridines with sodium nitrite in a DMSO paste in the presence of trifluoromethanesulfonic acid.

Role of copper in catalyzing aryl and heteroaryl-nitrogen (or -oxygen) bond formation under ligand-free and solvent-free conditions

Formation of aryl- or heteroaryl-nitrogen (or -oxygen) bonds under ligand and solvent-free conditions are highly selective to the presence of copper. While bromoarenes undergo C-N (or -O) coupling in stoichiometric presence of copper, heteroaryl bromides require only catalytic amounts of copper(I) salts depending on the position of bromo substituents. Such selectivity coupled with ligand and solvent-free protocols appear promising from the viewpoint of ecology and economy and are more attractive as compared to the existing protocols.

Pyridinium N-,(2'-azinyl)aminides: Regioselective synthesis of 2- alkylaminoazines

The regioselective alkylation of pyridinium-N-(2f'-azinil)aminides with alkyl halides under mild conditions is described. The alkylation, combined with a reduction of the N-N bond, allows an easy preparation of 2- alkylaminoazines. (C) 2000 Elsevier Science Ltd.