Synthesis and micellar mimic properties of bile acid trimers
Two fan-shaped bile acid trimers have been synthesized via Cu I-catalyzed azide-alkyne cycloaddition (CuAAC) 'click chemistry', and their extraction experiments of cresol red sodium (CR) and pyrene were investigated in the polar and non-polar solvents, respectively. The transmission electron microscopy (TEM) results showed that the homogenous hollow capsules formed with the diameter size range of 40-70 nm in a solution of water and acetone. Thus the amphiphilicity of fan-shaped bile acid trimers might be used as the promising candidate in biological and drug delivery applications.
Lu, Jinrong,Liu, Chulong,Hu, Jun,Ju, Yong
p. 1302 - 1305
(2013/03/14)
Olefins of the cholane series from deoxycholic and cholic acids
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Brieskorn,Mosandl
p. 118 - 127
(2007/10/02)
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