284664-88-6

Basic information

• Product Name: DL-LYSINE-4,4,5,5-D4 2HCL
• Synonyms: (2S)-2,6-bis(azanyl)hexanoic acid dihydrochloride;DL-LYSINE-4,4,5,5-D4 DIHYDROCHLORIDE, 98 ATOM % D;DL-LYSINE-4,4,5,5-D4 2HCL 99.1 G;99.1g;CICC1126
• CAS NO: 284664-88-6
• Molecular Formula: C6H10D4N2O2.2ClH
• Molecular Weight: 223.13
• EINECS: 211-518-3
• Product Categories: Alphabetical Listings;I-L;Stable Isotopes
• Mol File: 284664-88-6.mol

Chemical Properties

• Melting Point: 190 °C(lit.)
• Boiling Point: 369.8°C at 760 mmHg
• Flash Point: 177.4°C
• Appearance: /
• Vapor Pressure: 1.75E-06mmHg at 25°C
• CAS DataBase Reference: DL-LYSINE-4,4,5,5-D4 2HCL(CAS DataBase Reference)
• NIST Chemistry Reference: DL-LYSINE-4,4,5,5-D4 2HCL(284664-88-6)
• EPA Substance Registry System: DL-LYSINE-4,4,5,5-D4 2HCL(284664-88-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 284664-88-6(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
DL-LYSINE-4,4,5,5-D4 2HCL is used as a research compound for various applications in the field of biochemistry and molecular biology. The incorporation of deuterium atoms in the molecule allows researchers to study the behavior and interactions of this compound in different biological systems, providing valuable insights into the mechanisms of various biological processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, DL-LYSINE-4,4,5,5-D4 2HCL is used as a labeled compound for the development and optimization of drug candidates. The isotopically labeled nature of the compound enables researchers to track its distribution, metabolism, and excretion in the body, which can be crucial for understanding the pharmacokinetics and pharmacodynamics of potential drug molecules.
Used in Diagnostic Applications:
DL-LYSINE-4,4,5,5-D4 2HCL can also be employed in the development of diagnostic tools and tests. The labeled compound can be used as a tracer or marker in assays and other diagnostic techniques, allowing for the detection and quantification of specific biological processes or molecules of interest.
Used in Nutritional Studies:
In the field of nutrition, DL-LYSINE-4,4,5,5-D4 2HCL can be used to study the metabolism and utilization of lysine in the human body. The isotopically labeled compound can help researchers understand the role of lysine in various metabolic pathways and its impact on overall health and well-being.

InChI:InChI=1/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/i1D2,2D2;;

Upstream product

• 183069-80-9 [3,3,4,4,5,5-2H6]-ε-caprolactam 

Relevant articles and documents

Stereoselective synthesis of d4-(S)-Lysine from (S)-Serine

Tetradeuterated (S)-lysine can easily be obtained from protected (S)-serine in a few steps including a Cu-mediated cross coupling and subsequent platinum-catalysed deuteration.

Synthesis of - and Lysines

Starting from readily available cyclohexanone (1), synthesis of the title - and lysines (11) and (18) is described.Although direct incorporation of an amino or phthalimide group into the 2-bromohexanoic acid (5), which was derived from 1 in five steps. leading to 11 was unsuccessful due to hydrogen-deuterium scrambling, compound (11) was obtained in 86percent deuterium content via incorporation of an azido group and subsequent hydrogenation.Furthermore, compound (18) having 99percent deuterium content could be prepared by acid-catalysed deuterium exchange of 1 as a key-step.