- PRO-FRAGRANCE COMPOUNDS
-
A compound of Formula (I) wherein R1 represents a C3 to C20 hydrocarbon group derived from a fragrant alcohol of formula R1OH or from a fragrant aryl aldehyde or ketone of Formula (II), wherein: R2 is, independently, hydrogen atom, hydroxyl group, acetoxy group, -O(C=O)CH(CH3), optionally substituted C1-C6 alkyl group or C1-C6 alkoxy group, wherein any two of R2 may form an optionally substituted 5 or 6 membered ring, and R1 represents a radical derived from a fragrant alcohol of formula R1OH or from a fragrant aldehyde or from a fragrant aryl aldehyde or ketone of formula (II). The compounds are useful for example as a precursor for the prolonged delivery or release of fragrant compounds such as fragrant alcohols or aldehydes.
- -
-
Page/Page column 22
(2014/12/09)
-
- Synthesis and optical resolution of the floral odorant (±)-2,3- dihydro-2,5-dimethyl-1H-indene-2-methanol, and preparation of analogues
-
The title compound (±)-1, a recently discovered, valuable, floral-type odorant, has been synthesized by a straightforward procedure (Scheme 1), To determine the properties of the enantiomers of 1, their separation by preparative HPLC and the determination of their absolute configuration by X-ray crystallography were carried out (Figure). Furthermore, the analogues 2-6 were synthesized, either from differently methylated 2-methylin-dan-1-ones (Schemes 2 and 3) or, in the case of the 2,4,6-trimethylated homologue 6, by a completely different synthetic approach (Scheme 4). An evaluation of (+)-(S)-1, (-)-(R)-1, and (±)-1 showed only minor differences in terms of odor (Table).
- Vial, Christian,Bernardinelli, Gerald,Schneider, Philippe,Aizenberg, Michael,Winter, Beat
-
p. 3109 - 3117
(2007/10/03)
-