28646-40-4

Basic information

• Product Name: (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL
• Synonyms: (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL;[6aR,(-)]-6aβ,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-methanol;[6aR,10aR,(-)]-6a,7,10,10a-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-methanol;11-Hydroxy-trans-Δ8-tetrahydrocannabinol;11-Hydroxy-Δ8-tetrahydrocannabinol
• CAS NO: 28646-40-4
• Molecular Formula: C21H30O3
• Molecular Weight: 330.46
• Product Categories: Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 28646-40-4.mol

Chemical Properties

• Boiling Point: 429.8°Cat760mmHg
• Flash Point: 213.7°C
• Appearance: /
• Density: 1.071g/cm³
• Vapor Pressure: 3.77E-08mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL(28646-40-4)
• EPA Substance Registry System: (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL(28646-40-4)

Safety Data

• Hazardous Substances Data: 28646-40-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
(-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL is used as a therapeutic agent for various medical conditions due to its potential analgesic, anti-inflammatory, and neuroprotective properties. It may be particularly useful in the treatment of chronic pain, inflammation, and neurodegenerative disorders.
Used in Research and Development:
(-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL serves as a valuable compound for scientific research, particularly in the fields of pharmacology, neuroscience, and drug development. Its study can provide insights into the mechanisms of action of cannabinoids and their potential applications in medicine.
Used in the Cannabis Industry:
In the cannabis industry, (-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL is used as a component in the development of new cannabis products with potentially enhanced therapeutic effects. Its unique properties may contribute to the creation of novel formulations and delivery methods for medical and recreational use.
Used in Toxicology Studies:
(-)-11-HYDROXY-DELTA8-TETRAHYDROCANNABINOL is also utilized in toxicology research to better understand the safety and potential side effects of cannabis consumption. This knowledge can help inform regulations, guidelines, and consumer education regarding the responsible use of cannabis products.

InChI:InChI=1/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h8,11-12,16-17,22-23H,4-7,9-10,13H2,1-3H3/t16-,17-/m1/s1

Upstream product

• 5957-75-5 delta-8-tetrahydrocannabinol 
• 53865-18-2 11-oxo-6a,10a-trans-Δ⁸-THC 
• 61597-37-3 4-(1-hydroxy-1-methylethyl)-1-methoxy-1,4-cyclohexadiene 
• 500-66-3 Olivetol 
• 83889-49-0 9-β-bromo-11-oxo-6a,10a-trans-HHC 
• 6616-69-9 dl-6aα,7,10,10aα-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9(8H)-on 
• 6616-69-9 11-nor-9-keto-6a,10a-cis-HHC 

Relevant articles and documents

The synthesis of some 11-substituted tetrahydrocannabinol metabolites

9-Bromo-11-oxo-hexahydrocannabinol (5) was prepared from the ketocannabinoid 3b via the epoxysulfone 4.The dehydrobromination of the bromoaldehyde 5 could be controlled to give either the thermodinamically more stable Δ8-aldehyde 2c, or the Δ9-aldehyde 1c by an intramolecularly assisted elimination.Reduction of the unsaturated aldehydes gave the allylic alcohol metabolites 2a and 1a, respectively.