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1-(6-Benzofuranyl)-2-propanone is an organic compound with the chemical structure featuring a benzofuran ring attached to a propanone group. It is characterized by its light yellow oil appearance and is known for its role in the synthesis of various chemical compounds.

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  • 286836-34-8 Structure
  • Basic information

    1. Product Name: 1-(6-Benzofuranyl)-2-propanone
    2. Synonyms: 1-(6-Benzofuranyl)-2-propanone
    3. CAS NO:286836-34-8
    4. Molecular Formula: C11H10O2
    5. Molecular Weight: 174.1959
    6. EINECS: N/A
    7. Product Categories: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 286836-34-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 270.7±15.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.140±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: Chloroform, Methanol
    9. CAS DataBase Reference: 1-(6-Benzofuranyl)-2-propanone(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(6-Benzofuranyl)-2-propanone(286836-34-8)
    11. EPA Substance Registry System: 1-(6-Benzofuranyl)-2-propanone(286836-34-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 286836-34-8(Hazardous Substances Data)

286836-34-8 Usage

Uses

1. Used in Pharmaceutical Industry:
1-(6-Benzofuranyl)-2-propanone is used as a key intermediate in the preparation of aminoalkylbenzofurans, which are known as 5-HT2C agonists. These agonists have potential applications in the treatment of various central nervous system disorders, such as obesity, schizophrenia, and migraine.
2. Used in Chemical Synthesis:
1-(6-Benzofuranyl)-2-propanone serves as a versatile building block in the synthesis of a wide range of benzofuran-based compounds. These compounds find applications in various fields, including pharmaceuticals, agrochemicals, and materials science, due to their diverse biological activities and unique structural features.

Check Digit Verification of cas no

The CAS Registry Mumber 286836-34-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,6,8,3 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 286836-34:
(8*2)+(7*8)+(6*6)+(5*8)+(4*3)+(3*6)+(2*3)+(1*4)=188
188 % 10 = 8
So 286836-34-8 is a valid CAS Registry Number.

286836-34-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(1-benzofuran-6-yl)propan-2-one

1.2 Other means of identification

Product number -
Other names 1-(6-Benzofuranyl)-2-propanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:286836-34-8 SDS

286836-34-8Downstream Products

286836-34-8Relevant articles and documents

ADVANTAGEOUS BENZOFURAN COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT

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Page/Page column 249; 252; 274; 278; 279; 280; 310, (2021/12/31)

Pharmaceutically active benzofuran compositions for the treatment of mental disorders or for mental enhancement, including for entactogenic therapy. The present invention also includes benzofuran compounds, compositions, and methods for generally modulating central nervous system activity and treating central nervous system disorders.

Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists

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Page/Page column 34, (2010/11/08)

The present invention provides serotonergic aminoalkylbenzofurans of Formula (I): where R, R1, R2, R3, R4, R4′, R5, R5′, and R12 are as described in the specification.

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