288617-75-4 Usage
Uses
Used in Biochemistry Research:
(S)-N-Fmoc-2-(7'-octenyl) alanine is used as a research tool for the synthesis of peptides and proteins, allowing for the exploration of novel protein structures and functions. Its unique reactivity and structure provide insights into protein-ligand interactions and enzyme kinetics, contributing to a deeper understanding of biological processes.
Used in Chemical Biology:
In the field of chemical biology, (S)-N-Fmoc-2-(7'-octenyl) alanine is utilized as a building block for the development of bioactive molecules. Its modified structure enables the creation of new compounds with potential applications in drug discovery and the study of biological systems.
Used in Pharmaceutical Development:
(S)-N-Fmoc-2-(7'-octenyl) alanine is used as a component in the design and synthesis of new pharmaceuticals. Its unique properties can contribute to the development of drugs with improved efficacy and selectivity, particularly in the areas of peptide-based therapeutics and targeted drug delivery systems.
Used in Peptide Synthesis:
(S)-N-Fmoc-2-(7'-octenyl) alanine is used as a key ingredient in the synthesis of custom peptides for various applications, including diagnostics, therapeutics, and research. Its modified structure allows for the creation of peptides with specific properties, such as enhanced stability or binding affinity.
Used in Protein Engineering:
In protein engineering, (S)-N-Fmoc-2-(7'-octenyl) alanine is used as a building block for the creation of novel protein variants with altered functions or improved properties. This allows researchers to explore the structure-function relationships of proteins and develop proteins with tailored characteristics for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 288617-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,6,1 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 288617-75:
(8*2)+(7*8)+(6*8)+(5*6)+(4*1)+(3*7)+(2*7)+(1*5)=194
194 % 10 = 4
So 288617-75-4 is a valid CAS Registry Number.
InChI:InChI=1/C26H31NO4/c1-3-4-5-6-7-12-17-26(2,24(28)29)27-25(30)31-18-23-21-15-10-8-13-19(21)20-14-9-11-16-22(20)23/h3,8-11,13-16,23H,1,4-7,12,17-18H2,2H3,(H,27,30)(H,28,29)/t26-/m0/s1
288617-75-4Relevant articles and documents
Stabilized alpha helical peptides and uses thereof
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Sheet 2, (2016/05/19)
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF
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Paragraph 0087; 0156; 0157, (2014/05/20)
Provided are crystalline α, α-disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as well as optionally crystalline halogenated and deuterated analogs of the α, α-disubstituted amino acids and their salts; methods of making these, and methods of using these.
Robust asymmetric synthesis of unnatural alkenyl amino acids for conformationally constrained α-helix peptides
Aillard, Boris,Robertson, Naomi S.,Baldwin, Adam R.,Robins, Siobhan,Jamieson, Andrew G.
supporting information, p. 8775 - 8782 (2014/12/11)
The efficient asymmetric synthesis of unnatural alkenyl amino acids required for peptide 'stapling' has been achieved using alkylation of a fluorine-modified NiII Schiff base complex as the key step.
