289469-54-1

Basic information

• Product Name: 2-Chloro-4-Methyl thiazole-5-carbaldehyde
• Synonyms: 2-Chloro-4-Methyl thiazole-5-carbaldehyde;2-chloro-4-methyl-5-Thiazolecarboxaldehyde
• CAS NO: 289469-54-1
• Molecular Formula: C5H4ClNOS
• Molecular Weight: 161.60936
• Mol File: 289469-54-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-4-Methyl thiazole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-Methyl thiazole-5-carbaldehyde(289469-54-1)
• EPA Substance Registry System: 2-Chloro-4-Methyl thiazole-5-carbaldehyde(289469-54-1)

Safety Data

• Hazardous Substances Data: 289469-54-1(Hazardous Substances Data)

Upstream product

• 26847-01-8 2-chloro-4-methyl-1,3-thiazole 

Relevant articles and documents

AZOLE COMPOUNDS

The present invention provides a compound represented by the formula (I) wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, an optionally substituted thiol group or an optionally substituted amino group, A is an optionally substituted cyclic amino group or -NR2-W-D wherein R2 is a hydrogen atom or an alkyl group, W is a bond or a divalent acyclic hydrocarbon group, and D is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, X is an oxygen atom, a sulfur atom or an optionally substituted nitrogen atom, and Y is a bond or a divalent acyclic hydrocarbon group, or a salt thereof, which is useful for the prophylaxis or treatment of diabetic neuropathy and the like.

Pyridine compounds and their pharmaceutical use

A compound of formula (I) wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NOS(nitric oxide synthasey)-mediated diseases such as adult respiratory distress syndrome, myocarditis, synovitis, septic shock, insulin-ependent diabetes mellitus, ulcerative colitis, cerebral infarction, rheumatoid arthritis, osteoarthritis, osteoporosis, systemic lupus erythematosus, rejection by organ transplantation, asthma, pain, ulcer, and the like in human being and animals.