26847-01-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-methyl-thiazole is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into the development of new drugs, potentially enhancing their therapeutic properties and effectiveness.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-4-methyl-thiazole is employed as an intermediate in the production of pesticides and other agricultural chemicals. Its incorporation can contribute to the development of more effective and targeted pest control solutions.
Used in Dye Industry:
2-Chloro-4-methyl-thiazole is utilized in the synthesis of dyes, where its chemical properties can be leveraged to create a wide range of colorants for various applications, including textiles, plastics, and printing inks.
Used in Flavors and Fragrances Industry:
2-CHLORO-4-METHYL-THIAZOLE is also used in the preparation of flavors and fragrances, where its distinct aromatic properties can be harnessed to create unique scents and tastes for various consumer products.
Safety Considerations:
It is important to handle 2-chloro-4-methyl-thiazole with proper protective measures to prevent skin and eye irritation. Additionally, adherence to local regulations for storage and disposal is crucial to minimize potential environmental and health hazards associated with this chemical compound.

InChI:InChI=1/C4H4ClNS/c1-3-2-7-4(5)6-3/h2H,1H3

Upstream product

• 3029-48-9 thiocyanoacetone 
• 7647-01-0 hydrogenchloride 
• 1603-91-4 4-methylthiazol-2-ylamine 
• 110-46-3 isopentyl nitrite 
• 32497-10-2 4-methyl-2(3H)-thiazolone 
• 64-17-5 ethanol 

Downstream Products

• 90437-72-2 4-methyl-2-(morpholin-4-yl)thiazole-5-carbaldehyde 
• 85656-49-1 2-dimethylamino-4-methylthiazole-5-carbaldehyde 
• 292138-59-1 2-chloro-4-methylthiazole-5-sulfonyl chloride 
• 1351343-66-2 [(3R,4S)-4-(2,5-difluoro-phenyl)-1-(5-{(S)-1-[1-(4-methyl-thiazol-2-yl)piperidin-4-yl]ethoxy}pyrimidin-2-yl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 40615-11-0 1-(4-methyl-thiazol-2-yl)-piperazine 
• 289469-54-1 2-chloro-5-formyl-4-methylthiazole 
• 68194-81-0 [4-(4-methyl-thiazol-2-ylamino)-phenyl]-acetic acid 
• 693-95-8 4-Methylthiazole 
• 98484-42-5 2-(2-hydroxyethylamino)-4-methylthiazole 

Relevant academic research and scientific papers

THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF

Disclosed in the present invention are a new thiazole compound, particularly a compound represented by formula (I), a pharmaceutical composition thereof and applications thereof in the preparation of drugs for the treatment of diseases related to herpes simplex viruses.

Substituted 1-propiolylpiperazine compounds, their preparation and use

Substituted 1-propiolylpiperazine compounds corresponding to formula I in which X denotes N or C—R2, and n is an integer from 0 to 8, a method for producing such substituted 1-propiolylpiperazine compounds, pharmaceutical compositions containing such substituted 1-propiolylpiperazine compounds, and the use of such substituted 1-propiolylpiperazine compounds for modulating mGluR5 receptor activity or for treating or inhibiting pain and various other conditions, especially conditions at least partly mediated by the mGluR5 receptor.

Acetylenyl-pyrazolo-pyrimidine derivatives

The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.

SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS

The invention relates to substituted 1-propiolylpiperazines according to formula (I), to a method for the production thereof, medicaments containing said compounds and to the use thereof in the production of medicaments. In formula (I), X represents N or C-R2 and n corresponds to a value between 0-8.

Condensation reagents and a process for their preparation

The present invention relates to new bromo- and chlorothiazolium salts of the formula (I) in which R1, R2, R3, R4, n and X? have the meaning indicated in the disclosure, a process for their preparation, their use as condensation reagents, particularly as peptide coupling reagents, and intermediates for the preparation of these compounds.