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(S)-3-(Methylsulfonyl)pyrrolidine, also known as (S)-MSP or (S)-N-(methylsulfonyl)pyrrolidine, is a chiral chemical compound characterized by the molecular formula C6H13NO2S. It features a pyrrolidine ring with a methylsulfonyl group attached to one of its carbon atoms, making it a valuable building block in organic synthesis and a promising intermediate in various chemical processes, particularly within the pharmaceutical and agrochemical industries.

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  • 290328-57-3 Structure
  • Basic information

    1. Product Name: (S)-3-(Methylsulfonyl)pyrrolidine
    2. Synonyms: (S)-3-(Methylsulfonyl)pyrrolidine;(S)-3-(Methylsulfonyl)pyr...;(3S)-3-(Methylsulfonyl)pyrrolidine;(S)-3-(Methylsulfonyl)-pyrrolidine HCl;(3S)-3-methanesulfonylpyrrolidine
    3. CAS NO:290328-57-3
    4. Molecular Formula: C5H11NO2S
    5. Molecular Weight: 149.21134
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 290328-57-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 326.9±31.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.23±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 8.51±0.10(Predicted)
    10. CAS DataBase Reference: (S)-3-(Methylsulfonyl)pyrrolidine(CAS DataBase Reference)
    11. NIST Chemistry Reference: (S)-3-(Methylsulfonyl)pyrrolidine(290328-57-3)
    12. EPA Substance Registry System: (S)-3-(Methylsulfonyl)pyrrolidine(290328-57-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 290328-57-3(Hazardous Substances Data)

290328-57-3 Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-(Methylsulfonyl)pyrrolidine is used as a key intermediate in the synthesis of pharmaceutical compounds for its ability to be incorporated into the molecular structures of potential drugs. Its unique chiral properties allow for the creation of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and minimizing side effects.
Used in Agrochemical Industry:
In the agrochemical sector, (S)-3-(Methylsulfonyl)pyrrolidine serves as a versatile building block for the development of new agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness and selectivity, leading to improved crop protection and reduced environmental impact.
Used in Organic Synthesis:
(S)-3-(Methylsulfonyl)pyrrolidine is utilized as a valuable chemical intermediate in organic synthesis, enabling the creation of a wide range of other chemical compounds. Its presence in these reactions can facilitate the formation of complex molecular structures, contributing to the advancement of materials science and the discovery of novel chemical entities with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 290328-57-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,0,3,2 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 290328-57:
(8*2)+(7*9)+(6*0)+(5*3)+(4*2)+(3*8)+(2*5)+(1*7)=143
143 % 10 = 3
So 290328-57-3 is a valid CAS Registry Number.

290328-57-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-3-(Methylsulfonyl)pyrrolidine

1.2 Other means of identification

Product number -
Other names (3S)-3-methylsulfonylpyrrolidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:290328-57-3 SDS

290328-57-3Upstream product

290328-57-3Downstream Products

290328-57-3Relevant articles and documents

NOVEL HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE BCR-ABL INHIBITORS

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Page/Page column 46, (2017/12/09)

Disclosed is a compound of Formula (Ⅰ) or a pharmaceutically acceptable salt thereof, wherein the variables are described herein. Also disclosed is a process for the preparation of compounds, their pharmaceutical compositions comprising the same as an active ingredient, methods using said compositions in the treatment of various disorders, and use of the compounds in the manufacture of a medicament in inhibition of the enzymatic activities of ABL1, ABL2 and related chimeric proteins.

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