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2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is an organic chemical compound characterized by the molecular formula C10H12BF3O4. It is a boronic acid derivative featuring a phenyl ring with an isopropoxy and a trifluoromethoxy group substitution. 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is recognized for its role in organic synthesis, particularly as a reagent in the Suzuki-Miyaura cross-coupling reaction, which is instrumental in the formation of carbon-carbon bonds. Its applications extend to the pharmaceutical industry and materials science, where it is employed for the synthesis of a variety of organic compounds. 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is a versatile and significant chemical reagent, with broad applications in both organic chemistry research and industrial processes.

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  • 290832-43-8 Structure
  • Basic information

    1. Product Name: 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID
    2. Synonyms: 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID
    3. CAS NO:290832-43-8
    4. Molecular Formula: C8H8BF3O4
    5. Molecular Weight: 235.95
    6. EINECS: N/A
    7. Product Categories: Aryl;Organoborons
    8. Mol File: 290832-43-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 324.549 ºCat 760 mmHg
    3. Flash Point: 150.082 ºC
    4. Appearance: /
    5. Density: 1.406
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.465
    8. Storage Temp.: Inert atmosphere,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID(290832-43-8)
    12. EPA Substance Registry System: 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID(290832-43-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 290832-43-8(Hazardous Substances Data)

290832-43-8 Usage

Uses

Used in Organic Synthesis:
2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is used as a reagent in the Suzuki-Miyaura cross-coupling reaction for the formation of carbon-carbon bonds. This reaction is crucial in the synthesis of complex organic molecules, including pharmaceuticals and advanced materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is utilized for the synthesis of various organic compounds that have potential medicinal properties. Its role in creating new chemical entities is vital for the development of novel drugs and therapeutic agents.
Used in Materials Science:
2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is employed in materials science for the synthesis of organic compounds that can be used in the development of new materials with specific properties, such as improved conductivity, stability, or reactivity.
Used in Research and Development:
In the realm of research and development, 2-ISOPROPOXY-5-(TRIFLUOROMETHOXY)PHENYLBORONIC ACID is used as a key reagent for exploring new chemical reactions and mechanisms, contributing to the advancement of organic chemistry knowledge and its applications.

Check Digit Verification of cas no

The CAS Registry Mumber 290832-43-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,0,8,3 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 290832-43:
(8*2)+(7*9)+(6*0)+(5*8)+(4*3)+(3*2)+(2*4)+(1*3)=148
148 % 10 = 8
So 290832-43-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H8BF3O4/c1-15-7-3-2-5(16-8(10,11)12)4-6(7)9(13)14/h2-4,13-14H,1H3

290832-43-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-methoxy-5-(trifluoromethoxy)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names PC3084

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:290832-43-8 SDS

290832-43-8Relevant articles and documents

CHEMICAL COMPOUNDS

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Page/Page column 27, (2008/06/13)

This invention relates to biaryl ether derivatives of formula (I), wherein R1, R3, R4, X, W, Y and m are defined in the description, and to compositions containing them and the uses of such derivatives. The compounds of th

2-aryl indole derivative as antagonists of tachykinins

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, (2008/06/13)

The present invention relates to compounds of the formula (I): wherein R1a, R1b, R2, R3, R4, R5, X and n are defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis and postherpetic neuralgia.

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