292138-59-1

Basic information

• Product Name: 2-CHLORO-4-METHYL-THIAZOLE-5-SULFONYL CHLORIDE
• Synonyms: 2-CHLORO-4-METHYL-THIAZOLE-5-SULFONYL CHLORIDE
• CAS NO: 292138-59-1
• Molecular Formula: C4H3Cl2NO2S2
• Molecular Weight: 232.11
• Mol File: 292138-59-1.mol

Chemical Properties

• Boiling Point: 359.618 °C at 760 mmHg
• Flash Point: 171.291 °C
• Appearance: /
• Density: 1.694 g/cm³
• CAS DataBase Reference: 2-CHLORO-4-METHYL-THIAZOLE-5-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-METHYL-THIAZOLE-5-SULFONYL CHLORIDE(292138-59-1)
• EPA Substance Registry System: 2-CHLORO-4-METHYL-THIAZOLE-5-SULFONYL CHLORIDE(292138-59-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 292138-59-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-methyl-thiazole-5-sulfonyl chloride is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel drug molecules. Its unique structure and reactivity allow for the creation of therapeutic agents with specific properties, enhancing the range of available treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-4-methyl-thiazole-5-sulfonyl chloride serves as an intermediate in the production of various agrochemicals, including pesticides and herbicides. Its incorporation into these products helps improve their efficacy and selectivity, contributing to more effective crop protection strategies.
Used in Organic Synthesis:
As a versatile building block, 2-chloro-4-methyl-thiazole-5-sulfonyl chloride is used in organic synthesis for the creation of heterocyclic compounds. Its selective reactivity allows chemists to construct complex molecular structures with precision, facilitating the development of new compounds with potential applications in various fields.

Upstream product

• 7790-94-5 chlorosulfonic acid 
• 26847-01-8 2-chloro-4-methyl-1,3-thiazole 

Downstream Products

• 348086-67-9 2-chloro-4-methyl-1,3-thiazole-5-sulphonamide 

Relevant articles and documents

THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF

Disclosed in the present invention are a new thiazole compound, particularly a compound represented by formula (I), a pharmaceutical composition thereof and applications thereof in the preparation of drugs for the treatment of diseases related to herpes simplex viruses.

Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action

A series of congeners structurally related to pritelivir, N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide, a helicase-primase inhibitor for the treatment of herpes simplex virus infections, was prepared. The syn

Acetylenyl-pyrazolo-pyrimidine derivatives

The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.

Thiazolyl amide derivatives

The present invention relates to novel compounds, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.

Inverse thiazolylamide derivatives

The present invention relates to novel compounds, i.e. inverse thiazolylamide derivatives, to processes for their preparation and to their use as medicaments, in particular as antiviral medicaments.

Thiazolyl urea derivatives and their utilization as antiviral agents

The present invention relates to thiazolylurea derivatives, a process for their preparation, and their use as pharmaceuticals, in particular as antiviral pharmaceuticals.