29241-60-9

Basic information

• Product Name: 2-Chloro-3-methyl-5-bromopyridine
• Synonyms: 5-BROMO-2-CHLORO-3-PICOLINE;5-BROMO-2-CHLORO-3-METHYLPYRIDINE;2-CHLORO-3-METHYL-5-BROMO PYRIDINE;2-CHLORO-5-BROMO-3-PICOLINE;2-Chloro-5-bromo-3-methylpyridine;5-BROMO-2-CHLORO-3-PICOLINE (5-BROMO-2-CHLORO-3-METHYLPYRIDINE);5-Bromo-2-chloro-3-methylpyridine ,98%;5-Bromo-2-chloro-3-picoline,98%
• CAS NO: 29241-60-9
• Molecular Formula: C₆H₅BrClN
• Molecular Weight: 206.47
• Product Categories: compounds of pyridine;Pyridine;Pyridine series;Pyridines;Boronic Acid;Heterocycle-Pyridine series
• Mol File: 29241-60-9.mol

Chemical Properties

• Melting Point: 40-44 °C
• Boiling Point: 78°C/3mmHg(lit.)
• Flash Point: 95.5 °C
• Appearance: /Solid
• Density: 1.6567 (rough estimate)
• Vapor Pressure: 0.0817mmHg at 25°C
• Refractive Index: 1.5400 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1?+-.0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-3-methyl-5-bromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-methyl-5-bromopyridine(29241-60-9)
• EPA Substance Registry System: 2-Chloro-3-methyl-5-bromopyridine(29241-60-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 29241-60-9(Hazardous Substances Data)

Usage

Chemical Properties

white to light beige crystalline powder

InChI:InChI=1/C6H5BrClN/c1-4-2-5(7)3-9-6(4)8/h2-3H,1H3

Upstream product

• 89488-30-2 5-bromo-2-hydroxy-3-methyl pyridine 
• 22280-56-4 2-chloro-3-methyl-5-nitropyridine 
• 38186-82-2 6-chloro-5-methylpyridin-3-amine 

Downstream Products

• 923957-53-3 (1S,6R)-3-(6-chloro-5-methyl-pyridin-3-yl)-3,8-diaza-bicyclo[4.2.0]octane-8-carboxylic acid tert-butyl ester 
• 370882-95-4 tert-butyl (1S,6R)-8-(6-chloro-5-methyl-3-pyridinyl)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate 
• 370883-00-4 tert-butyl (1R,6S)-8-(6-chloro-5-methyl-3-pyridinyl)-3,8-diazabicyclo[4.2.0]octane-3-carboxylate 
• 898229-26-0 methyl 1-(5-bromo-3-methylpyridin-2-yl)piperidine-4-carboxylate 
• 1443684-50-1 2-(2-chloro-6-fluorophenyl)-5-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-1H-pyrrolo[2,3-b]pyridine 
• 1393126-10-7 5-bromo-3-methyl-2-(4-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine 
• 1393126-09-4 5-methyl-6-(4-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-3-ol 
• 1353530-22-9 (R)-2-chloro-5-[(2,3-dimethyl-1,3-dioxolan-4-yl)methyl]-3-methylpyridine 
• 1353530-21-8 (R)-3-(6-chloro-5-methylpyridin-3-yl)propane-1,2-diol 
• 1353530-20-7 5-allyl-2-chloro-3-methylpyridine 
• 1243245-77-3 tert-butyl 2-(6-chloro-5-methylpyridin-3-yl)acetate 
• 1243245-92-2 diethyl 2-(6-chloro-5-methylpyridin-3-yl)malonate 
• 370880-43-6 tert-butyl (3AR,6AR)-5-(6-chloro-5-methyl-3-pyridinyl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate 
• 245765-66-6 (5-bromo-6-methylpyridin-2-yl)methylamine 

Relevant articles and documents

Heterocyclic substituted aminoazacycles useful as central nervous system agents

Heterocyclic substituted aminoazacyclic compounds of the formula (I):Z-R3, wherein Z is a defined aminoazacycle and R3 is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.

Diazabicyclic central nervous system active agents

Compounds of formula I pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.

Synthesis of dihalopicoline N-oxides and their 4-nitro derivatives

Three aminohalo-substituted α- and β-picolines, six dihalo-substituted α- and β-picolines, six dihalo-substituted α- and β-picoline N-oxides and six respective dihalo-4-nitropicoline N-oxides were synthesized in excellent yields. Some properties of the products were reported. 1997 Plenum Publishing Corporation.