297180-15-5

Basic information

• Product Name: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one
• Synonyms: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one;5-bromo-5'-phenyl-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-2(1H)-one
• CAS NO: 297180-15-5
• Molecular Formula: C15H10BrN3OS
• Molecular Weight: 360.23
• Mol File: 297180-15-5.mol

Chemical Properties

• Appearance: /
• Density: 1.76±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: Soluble in DMSO (up to 20 mg/ml).
• PKA: 0.44±0.20(Predicted)
• Stability: Stable for 1 year from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
• CAS DataBase Reference: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one(297180-15-5)
• EPA Substance Registry System: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one(297180-15-5)

Safety Data

• Hazardous Substances Data: 297180-15-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one is used as a potential therapeutic agent for the treatment of various diseases. Its specific application reason is not provided in the materials, but its unique structure suggests that it may have properties that can be exploited for medicinal purposes.
Used in Chemical Research:
5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one can be used as a research compound in the field of organic chemistry. Its synthesis and properties can be studied to gain insights into the behavior of similar compounds and to develop new synthetic methods or applications.
Used in Material Science:
5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one may also find applications in the field of material science, particularly in the development of new materials with specific properties. Its unique structure could potentially be utilized to create materials with tailored characteristics for various applications.

References

1) Sandoval?et al.?(2010),?Identification and characterization of small compound inhibitors of human FATP2; Biochem. Pharmacol.?79?990 2) Ahowesso?et al.?(2015),?Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death; Biochem. Pharmacol.?98?167 3) Zhang?et al.?(2018),?Adipocyte-derived lipids mediate melanoma progression via FATP proteins; Cancer Discov.?8?1006 br />

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