299168-49-3

Basic information

• Product Name: AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID
• Synonyms: AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID;2-AMINO-2-(4-ETHOXYPHENYL)ACETIC ACID;2-(4-Ethoxyphenyl)glycine;RS-4-(ethoxy)-phenylglycine
• CAS NO: 299168-49-3
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.22
• Product Categories: pharmacetical
• Mol File: 299168-49-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID(299168-49-3)
• EPA Substance Registry System: AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID(299168-49-3)

Safety Data

• Hazardous Substances Data: 299168-49-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID is utilized as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new medications with potential therapeutic benefits.
Used in Chemical Research and Drug Discovery:
In the field of chemical research, AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID serves as a valuable compound for studying its properties and exploring its potential applications. It may contribute to the discovery of novel drug candidates and the advancement of pharmaceutical science.
The specific applications and formulations of AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID may vary depending on the requirements of the industry and the intended use of the final product. Its versatility and solubility in multiple solvents make it a promising compound for further exploration and development in various sectors.

Upstream product

• 32462-30-9 (S)-hydroxyphenylglycine 
• 75-03-6 ethyl iodide 
• 22818-40-2 D-4-hydroxyphenylglycine 

Relevant articles and documents

Palladium(II) complexes of chiral tridentate nitrogen pybox ligands

A series of mono-and di-cationic palladium(II) complexes containing different chiral tridentate nitrogen ligands, pybox, have been prepared [pybox = 2,6-bis[4′-(S)-iPr (or Ph, or Bz or p-EtOC6H4)oxazoline-2′-y1]pyridine (1-4), respectively]. The molecular structures for two of these, [Pd(CH3CN)(2)](BF4)2 (6) and [Pd(PPh3)(3)](BF4)2 (21g), have been determined by X-ray diffraction and show no major steric hindrance in the fourth coordination position. In connection with the aldol reaction of CNCH2CO2Me with PhCHO, several new isonitrile PdII complexes have also been prepared. It is shown that, under catalytic conditions, the chiral tridentate pybox ligand is completely displaced, thus explaining its failure as a chiral auxiliary. Preparative details for a series of chiral Pd(L)(3)n+(BF4)n (21) complexes [L = 4-methylpyridine, 2,6-dimethylpyridine, 4-methyl aniline, H2NCH2CH(OMe)2, H2NCH2CH2OH, H2N(CH2)5CH3, N-3, HCO-2, Cl-] are given, as are preparative details for some model PdII acetonitrile complexes with chiral phosphorus and nitrogen chelating ligands. For 6, i.e. PdC25H22N4O2B2F8, the crystals are monoclinic with space group P21 (No. 4), a = 13.582(6) A, b = 13.826(6) A, c = 14.667(6) A, β = 97.28(3)°°, V = 2732(2) A3, Z = 4. For 21g, i.e. C43H38B2F8N3O2P2Pd, the crystals are orthorhombic with space group, P212121, a = 10.616(4) A, b = 16.774(2) A, c = 23.086(4) A, V = 4111(3) A3, Z = 4.

Challenge toward structural complexity using asymmetric catalysis: Target-oriented development of catalytic enantioselective Diels-Alder reaction

(Chemical Equation Presented) A new method for the catalytic enantioselective Diels-Alder reaction using polysubstituted silyl enol ethers as dienes is described. High enantioselectivity (up to 92% ee) was produced using a catalyst generated from FeBr3 and AgSbF6 in a 1:2 ratio and aryl-pybox (aryl = Ph or p-ethoxyphenyl). This reaction should facilitate the enantioselective synthesis of polycyclic acylphloroglucinols such as hyperforin or garsubellin A, which are currently of interest from synthetic and medicinal points of view.