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304452-55-9

N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 304452-55-9 Structure

  • Basic information

    1. Product Name: N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide
    2. Synonyms: N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide;N-(2-methyl-5-nitrophenyl)biphenyl-4-carboxamide
    3. CAS NO:304452-55-9
    4. Molecular Formula: C20H16N2O3
    5. Molecular Weight: 332.35264
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 304452-55-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide(304452-55-9)
    11. EPA Substance Registry System: N-(2-methyl-5-nitrophenyl)-4-biphenylcarboxamide(304452-55-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 304452-55-9(Hazardous Substances Data)

304452-55-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 304452-55-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,4,4,5 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 304452-55:
(8*3)+(7*0)+(6*4)+(5*4)+(4*5)+(3*2)+(2*5)+(1*5)=109
109 % 10 = 9
So 304452-55-9 is a valid CAS Registry Number.

304452-55-9Relevant articles and documents

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo

Vesci, Loredana,Milazzo, Ferdinando Maria,Stasi, Maria Antonietta,Pace, Silvia,Manera, Francesco,Tallarico, Carlo,Cini, Elena,Petricci, Elena,Manetti, Fabrizio,De Santis, Rita,Giannini, Giuseppe

, p. 368 - 379 (2018/08/17)

Small series of acylguanidine and acylthiourea derivatives were synthesized in gram-scale and assayed for their ability to modulate the Hh signalling pathway. In vitro studies showed a low micromolar inhibitory activity toward tumor cell lines, while the oral administration revealed an excellent ADME profile in vivo. Compound 5 emerged as the most active and safe inhibitor of colon cancer cells both in vitro and in a xenograft mouse model. Based on these data, 5 could be prioritized to further development with the perspective of clinical studies.

Acyl Guanidine Derivatives Modulating The Hedgehog Protein Signaling Pathway

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Page/Page column 16, (2012/08/08)

The present invention relates to acyl guanidine derivatives modulating the hedgehog protein signaling pathway to be used as drugs, in particular for treating diseases involving a tissue dysfunction associated with a deregulation of the hedgehog protein signaling pathway, as well as to pharmaceutical compositions containing same. The present invention also relates to novel acyl guanidine derivatives as such.

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