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1-Ethyl-1H-pyrazole-4-carbaldehyde, also known as ethyl pyrazole carbaldehyde, is a heterocyclic chemical compound with the molecular formula C8H10N2O. It features a pyrazole ring with an ethyl group attached to the nitrogen atom and a formyl group attached to the carbon atom at position 4. 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE is recognized for its unique structure and reactivity, making it a valuable intermediate in organic synthesis and an important compound in the fields of medicinal and chemical research.

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  • 304903-10-4 Structure
  • Basic information

    1. Product Name: 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE
    2. Synonyms: TIMTEC-BB SBB000003;BUTTPARK 121\06-90;ART-CHEM-BB B000402;CHEMBRDG-BB 4003132;1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE;1-ETHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE;AKOS PAO-0266;AKOS B000402
    3. CAS NO:304903-10-4
    4. Molecular Formula: C6H8N2O
    5. Molecular Weight: 124.14
    6. EINECS: 1312995-182-4
    7. Product Categories: ALDEHYDE;Aldehydes;Pyrazoles & Triazoles;Pyrazoles & Triazoles
    8. Mol File: 304903-10-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 72°C/1.8mm
    3. Flash Point: 92.8 °C
    4. Appearance: /
    5. Density: 1.1 g/cm3
    6. Vapor Pressure: 0.0678mmHg at 25°C
    7. Refractive Index: 1.541
    8. Storage Temp.: Room temperature.
    9. Solubility: N/A
    10. PKA: 0.19±0.10(Predicted)
    11. CAS DataBase Reference: 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE(304903-10-4)
    13. EPA Substance Registry System: 1-ETHYL-1H-PYRAZOLE-4-CARBALDEHYDE(304903-10-4)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 304903-10-4(Hazardous Substances Data)

304903-10-4 Usage

Uses

Used in Pharmaceutical Industry:
1-Ethyl-1H-pyrazole-4-carbaldehyde is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Ethyl-1H-pyrazole-4-carbaldehyde serves as a crucial intermediate in the synthesis of agrochemicals. Its reactivity and structural properties make it suitable for the creation of compounds that can be used in agricultural applications, such as pesticides and herbicides.
Used in Organic Synthesis:
1-Ethyl-1H-pyrazole-4-carbaldehyde is used as a versatile intermediate in organic synthesis for the preparation of a wide range of organic compounds. Its ability to participate in various chemical reactions makes it an essential tool for chemists in developing new organic molecules with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 304903-10-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,4,9,0 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 304903-10:
(8*3)+(7*0)+(6*4)+(5*9)+(4*0)+(3*3)+(2*1)+(1*0)=104
104 % 10 = 4
So 304903-10-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O/c1-2-8-4-6(5-9)3-7-8/h3-5H,2H2,1H3

304903-10-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Ethyl-1H-pyrazole-4-carbaldehyde

1.2 Other means of identification

Product number -
Other names 1-Ethyl-1H-Pyrazole-4-Carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:304903-10-4 SDS

304903-10-4Relevant articles and documents

Synthesis of heterocyclic compounds from 4-formylpyrazoles

Mortikov,Rodinovskaya,Fedorov,Shestopalov,Belyakov

, p. 443 - 456 (2015/02/02)

Formylation of pyrazole and 2,5-dimethylpyrazole gave a number of pyrazole-containing aldehydes, which can be used to obtain chromenes, tetrahydrochromenes, 1,4-dihydropyrano[2,3-c]pyrazoles, pyrano[3,2-c]chromenes, thiochromeno[4,3-b]pyrans, pyrano[3,2-c

SMALL MOLECULE INHIBITORS OF IL-6 AND USES THEREOF

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Paragraph 00702; 00932, (2013/03/26)

In one aspect, the invention relates to substituted 2-(lH-indol-3-yl)ethanol analogs and substituted 3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indole analogs, derivatives thereof, and related compounds, which are useful as inhibitors of IL-6 mediated activation of the Jak2/STAT3 pathway; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with a IL6 dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

OPTICALLY ACTIVE TETRAHYDRONAPHTHALENE DERIVATIVE

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Page/Page column 17, (2010/11/28)

A compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate thereof or a solvate thereof, which shows not only a C5a receptor antagonistic activity but also high activity in the biological availability, as

Synthesis of 1-ethylpyrazole-4-carbaldehydes, 1,1′-methylenebis(3,5- dimethylpyrazole-4-carbaldehyde), and Schiff bases derived therefrom

Potapov,Khlebnikov,Ogorodnikov

, p. 550 - 554 (2007/10/03)

New pyrazole-containing aldehydes, 1-ethylpyrazole-4-carbaldehyde, 1-ethyl-3,5-dimethylpyrazole-4-carbaldehyde, and 1,1′-methylenebis(3,5- dimethylpyrazole-4-carbaldehyde), were synthesized by the Vilsmeier reaction. Their reactions with primary amines (a

BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF

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Page 113, (2012/10/08)

Compounds of the general formula (I): or salts thereof, which exhibit CCR5 antagonism and exert preventive and therapeutic effects against HIV infections: wherein R1 is a 5- to 6-membered aromatic ring which bears a substituent represented by the general formula: R-Z1-X-Z2- (wherein R1 is hydrogen or optionally substituted hydrocarbyl; X is optionally substituted alkylene; and Z1 and Z2 are each a heteroatom) and may be further substituted, with R being optionally bonded to the aromatic ring to form another ring; Y is optionally substituted imino; and R2 and R3 are each optionally substituted aliphatic hydrocarbyl or an optionally substituted hetero-alicyclic group.

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