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2(3H)-Phenanthrenone, 4,4a,9,10-tetrahydro-7-methoxy-4a-(phenylmethyl)-, (4aS)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

305822-55-3

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  • 2(3H)-Phenanthrenone, 4,4a,9,10-tetrahydro-7-methoxy-4a-(phenylmethyl)-, (4aS)-

    Cas No: 305822-55-3

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305822-55-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 305822-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,8,2 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 305822-55:
(8*3)+(7*0)+(6*5)+(5*8)+(4*2)+(3*2)+(2*5)+(1*5)=123
123 % 10 = 3
So 305822-55-3 is a valid CAS Registry Number.

305822-55-3Relevant articles and documents

GLUCOCORTICOID RECEPTOR MODULATORS

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, (2018/03/25)

The present invention provides non-steroidal compounds of formula I which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compos

Glucocorticoid receptor modulators

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Page 26, (2010/01/31)

The present invention provides non-steroidal compounds of Formula I, and prodrugs and pharmaceutically acceptable salts thereof, which are selective modulators (e.g., agonists, partial agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides processes for preparing these compounds.

Glucocorticoid receptor modulators

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Example 3, (2010/11/29)

The present invention provides non-steroidal compounds of Formula I, including prodrugs and pharmaceutically acceptable salts thereof, which are selective modulators (e.g., agonists, partial agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides processes for preparing these compounds.

Discovery of potent, nonsteroidal, and highly selective glucocorticoid receptor antagonists

Morgan, Bradley P.,Swick, Andrew G.,Hargrove, Diane M.,LaFlamme, Janet A.,Moynihan, Melinda S.,Carroll, Richard S.,Martin, Kelly A.,Lee, Eunsun,Decosta, Debra,Bordner, Jon

, p. 2417 - 2424 (2007/10/03)

An approach to the computer-assisted, pharmacophore design of nonsteroidal templates for the glucocorticoid receptor (GR) that contained an element of pseudo-C2 symmetry was developed. The enatiomer of the initial design, 1Ra, and not the designed molecul

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