Welcome to LookChem.com Sign In|Join Free

CAS

  • or

305864-19-1

2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

305864-19-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 305864-19-1 Structure

  • Basic information

    1. Product Name: 2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE
    2. Synonyms: 2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE;2-{[(4-bromophenyl)amino]methylidene}-5,5-dimethylcyclohexane-1,3-dione
    3. CAS NO:305864-19-1
    4. Molecular Formula: C15H16BrNO2
    5. Molecular Weight: 322.2
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 305864-19-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE(305864-19-1)
    11. EPA Substance Registry System: 2-(((4-BROMOPHENYL)AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE(305864-19-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 305864-19-1(Hazardous Substances Data)

305864-19-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 305864-19-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,8,6 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 305864-19:
(8*3)+(7*0)+(6*5)+(5*8)+(4*6)+(3*4)+(2*1)+(1*9)=141
141 % 10 = 1
So 305864-19-1 is a valid CAS Registry Number.

305864-19-1Downstream Products

305864-19-1Relevant articles and documents

The synthesis, biological evaluation and structure-activity relationship of 2-phenylaminomethylene-cyclohexane-1,3-diones as specific anti-tuberculosis agents

Rather, Muzafar Ahmad,Lone, Ali Mohd,Teli, Bisma,Bhat, Zubair Shanib,Singh, Paramjeet,Maqbool, Mubashir,Shairgojray, Bashir Ahmad,Dar, Mohd Jamal,Amin, Shajrul,Yousuf, Syed Khalid,Bhat, Bilal A.,Ahmad, Zahoor

supporting information, p. 2133 - 2141 (2017/11/22)

The present study utilised whole cell based phenotypic screening of thousands of diverse small molecules against Mycobacterium tuberculosis H37Rv (M. tuberculosis) and identified the cyclohexane-1,3-dione-based structures 5 and 6 as hits. The selected hit molecules were used for further synthesis and a library of 37 compounds under four families was synthesized for lead generation. Evaluation of the library against M. tuberculosis lead to the identification of three lead antituberculosis agents (37, 39 and 41). The most potential compound, 2-(((2-hydroxyphenyl)amino)methylene)-5,5-dimethylcyclohexane-1,3-dione (39) showed an MIC of 2.5 μg mL-1, which falls in the range of MICs values found for the known antituberculosis drugs ethambutol, streptomycin and levofloxacin. Additionally, this compound proved to be non-toxic (20% inhibition at 50 μM concentration) against four human cell lines. Like first line antituberculosis drugs (isoniazid, rifampicin and pyrazinamide) this compound lacks activity against general Gram positive and Gram negative bacteria and even against M. smegmatis; thereby reflecting its highly specific antituberculosis activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 305864-19-1