312489-60-4

Basic information

• Product Name: 1H-Azepine-3,4,6-triol, hexahydro-, (3R,4R,6S)- (9CI)
• Synonyms: 1H-Azepine-3,4,6-triol, hexahydro-, (3R,4R,6S)- (9CI)
• CAS NO: 312489-60-4
• Molecular Formula: C6H13NO3
• Molecular Weight: 147.17232
• Product Categories: ALCOHOL
• Mol File: 312489-60-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Azepine-3,4,6-triol, hexahydro-, (3R,4R,6S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Azepine-3,4,6-triol, hexahydro-, (3R,4R,6S)- (9CI)(312489-60-4)
• EPA Substance Registry System: 1H-Azepine-3,4,6-triol, hexahydro-, (3R,4R,6S)- (9CI)(312489-60-4)

Safety Data

• Hazardous Substances Data: 312489-60-4(Hazardous Substances Data)

Upstream product

• 269741-53-9 6-azido-3,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hexofuranose 
• 4005-46-3 (1R)-1-[(3aR,5R,6aR)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol 
• 22323-55-3 3-deoxy-1,2-O-isopropylidene-6-O-tosyl-α-D-xylo-hexofuranose 
• 162427-40-9 3-deoxygalactose (α-furanose) 
• 22248-86-8 3-deoxy-1,2:5,6-di-O-isopropylidene-β-D-arabino-hexofuranose 
• 284031-19-2 3-deoxy-1,2-O-isopropylidene-6-O-tosyl-β-D-arabino-hexofuranose 
• 58475-16-4 [(2R)-2-[(3aR,5S,6aR)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d] [1,3]dioxol-5-yl]-2-hydroxy-ethyl]4-methylbenzenesulfonate 
• 4005-46-3 3-deoxy-1,2-O-isopropylidene-D-glucose 
• 79645-44-6 3-deoxy-L-xylo-hexono-1,4-lactone 
• 284031-29-4 3-deoxy-1,2-O-isopropylidene-6-O-tosyl-α-L-xylo-hexofuranose 
• 943032-29-9 (3S,4R,6S)-1-benzyl-6-O-benzyl-3,4-O-cyclohexylidene-3,4,6-trihydroxyazepane 
• 943032-30-2 (3S,4R,6R)-1-benzyl-6-O-benzyl-3,4-O-cyclohexylidene-3,4,6-trihydroxyazepane 
• 943032-35-7 (3S,4R,6R)-6-O-acetyl-1-benzyl-3,4-O-cyclohexylidene-3,4,6-trihydroxyazepane 
• 848837-64-9 C₁₄H₂₂O₆ 

Relevant articles and documents

Expeditious synthesis of tri- and tetrahydroxyazepanes from D-(-)-quinic acid as potent glycosidase inhibitors

(Chemical Equation Presented) Several new stereoisomers of 3,4,6-trihydroxyazepanes and 7-hydroxymethyl-3,4,5-trihydroxyazepanes as well as known 3,4,5-trihydroxyazepanes were synthesized as potent glycosidase inhibitors from D-(-)-quinic acid in an effic

Chemo-enzymatic synthesis of polyhydroxyazepanes

Galactose oxidase (EC 1.1.3.9, GAO) is an extracellular copper-containing enzyme that utilizes molecular oxygen to convert the C6-primary hydroxyl moiety of D-galactopyranosides to hydrated aldehydes. Subsequent dehydratative coupling with hydroxylamines produces oximes (3a-f), which, when subjected to conditions of hydrogenolysis, give rise to polyhydroxyazepanes (11-17).

Syntheses of sugar-related trihydroxyazepanes from simple carbohydrates and their activities as reversible glycosidase inhibitors

Five diastereomeric trideoxy-1,6-iminohexitols were synthesised, and their inhibitory activities were determined against selected glycosidases. For comparison, 1,4,5-trideoxy-1,5-imino-D-lyxo-hexitol, the 4-deoxy derivative of 1-deoxymannojirimicin, was prepared by enzymatic isomerisation of 6-azido-3,6-dideoxy-D-ribo-hexose into the corresponding 2-ulose and subsequent hydrogenation accompanied by intramolecular reductive amination. (C) 2000 Elsevier Science Ltd.