312623-94-2 Usage
Uses
Used in Metabolic Research:
D-[6-13C]fructose is used as a tracer in metabolic research for tracking the metabolic fate of fructose within biochemical pathways. The 13C labeling at the 6th carbon position allows researchers to monitor the incorporation of fructose into various metabolic intermediates and products, providing insights into the regulation and dynamics of carbohydrate metabolism.
Used in Glucose Metabolism Studies:
D-[6-13C]fructose is used as a tool in glucose metabolism studies to differentiate between endogenously produced fructose and exogenously supplied fructose. This distinction is crucial for understanding the distinct metabolic effects and contributions of these two sources of fructose in the body.
Used in Medical and Nutritional Research:
D-[6-13C]fructose is used as a research compound in medical and nutritional studies to investigate the role of fructose in metabolic diseases, such as diabetes, obesity, and non-alcoholic fatty liver disease. The stable isotope labeling enables the assessment of fructose metabolism and its impact on overall health and disease progression.
Used in Pharmaceutical Development:
D-[6-13C]fructose is used as a research tool in pharmaceutical development for the discovery and testing of new drugs targeting carbohydrate metabolism. The isotopically labeled compound can help in understanding the mechanisms of action and potential side effects of these drugs, ultimately contributing to the development of more effective treatments for metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 312623-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,6,2 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 312623-94:
(8*3)+(7*1)+(6*2)+(5*6)+(4*2)+(3*3)+(2*9)+(1*4)=112
112 % 10 = 2
So 312623-94-2 is a valid CAS Registry Number.
312623-94-2Relevant articles and documents
Strong binding affinity of d-allulose and allulosides to boronic acids and the structural characterization of their sugar-boronate complexes
Arimitsu, Kenji,Iwasaki, Hiroki,Kimura, Hiroyuki,Yasui, Hiroyuki
supporting information, p. 1470 - 1474 (2021/08/04)
As sugars form complexes with boronic acids, some sugars are used as additives for boron-containing pharmaceuticals. The binding constants of the rare sugar D-allulose with boronic acids were measured, and these showed the highest hitherto reported binding-affinity values for sugars. An NMR study clarified that D-allulose in aqueous solution forms complexes exclusively via the reaction of the 2,3-hydroxy groups of α-allulofuranose. Conversely, in organic solvents, D-allulose forms a single complex derived from the 3,5-hydroxy groups of β-allulopyranose.
Synthesis of natural/13C-enriched D-tagatose from natural/13C-enriched D-fructose
Suchy, Mojmír,Charlton, Thomas A.,Ben, Robert N.,Shuhendler, Adam J.
, (2021/07/26)
A concise, easily scalable synthesis of a rare ketohexose, D-tagatose, was developed, that is compatible with the preparation of D-[UL-13C6]tagatose. Epimerization of the widely available and inexpensive ketohexose D-fructose at the C-4 position via an oxidation/reduction (Dess-Martin periodinane/NaBH4) was a key step in the synthesis. Overall, fully protected natural D-tagatose (3.21 g) was prepared from D-fructose (9 g) on a 50 mmol scale in 23% overall yield, after five steps and two chromatographic purifications. D-[UL-13C6]Tagatose (92 mg) was prepared from D-[UL-13C6]fructose (465 mg, 2.5 mmol) in 16% overall yield after six steps and four chromatographic purifications.
