312631-76-8 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-bromobenzyl)-1H-benzimidazole is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic benefits.
Used in Organic Synthesis:
As a building block in organic synthesis, 1-(2-bromobenzyl)-1H-benzimidazole is used for the creation of new materials and compounds. Its unique structure allows for further functionalization and modification, making it a valuable component in the design and synthesis of novel organic molecules.
Used in Anticancer Applications:
1-(2-bromobenzyl)-1H-benzimidazole has demonstrated potential as an anti-cancer agent. It is studied for its inhibitory effects on certain enzymes that play a role in cancer cell proliferation and survival, making it a promising candidate for the development of targeted cancer therapies.
Used in Enzyme Inhibition Research:
1-(2-bromobenzyl)-1H-benzimidazole's ability to inhibit specific enzymes has made it a subject of interest in the field of enzyme inhibition research. 1-(2-bromobenzyl)-1H-benzimidazole is used as a tool to study enzyme function and to develop new inhibitors that could be applied in therapeutic strategies for various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 312631-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,6,3 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 312631-76:
(8*3)+(7*1)+(6*2)+(5*6)+(4*3)+(3*1)+(2*7)+(1*6)=108
108 % 10 = 8
So 312631-76-8 is a valid CAS Registry Number.
312631-76-8Relevant articles and documents
Dual Catalysis in Domino N-Benzylation/Intramolecular C-H Arylation: Regio- and Chemoselective Synthesis of Annelated Nitrogen Heterocycles
Laha, Joydev K.,Dayal, Neetu,Singh, Swati,Bhimpuria, Rohan
, p. 5469 - 5475 (2014/10/15)
A general method has been developed for the synthesis of fused nitrogen heterocycles by using a domino N-benzylation/C-H arylation reaction sequence. The details and yields of the domino process were compared with those of the two-step literature protocol
Intramolecular cyclization reaction - Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction
Majumdar, Krishna C.,Debnath, Pradip,Taher, Abu,Pal, Amarta K.
, p. 325 - 332 (2008/09/20)
Intramolecular CH arylation of pyrone, pyridone, uracil, imidazole, and benzimidazole derivatives are carried out in the presence of a Pd catalyst to form potentially bioactive fused heterocyclic compounds, whereas the n-Bu 3SnH-mediated aryl radical cyclization of the precursors 3 afforded mainly halogen-reduced uncyclized products.
