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4-Fluorobenzylzinc chloride is a chemical compound that consists of a zinc atom bonded to a 4-fluorobenzyl group and a chloride ion. It is a versatile reagent in organic synthesis, known for its ability to form carbon-carbon bonds through the Barbier reaction.

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  • 312693-07-5 Structure
  • Basic information

    1. Product Name: 4-FLUOROBENZYLZINC CHLORIDE
    2. Synonyms: 4-FLUOROBENZYLZINC CHLORIDE;4-FLUOROBENZYLZINC CHLORIDE, 0.5M SOLUTI ON IN TETRAHYDROFURAN;4-fluorobenzylzinc chloride solution;4-Fluorobenzylzinc chloride solution 0.5 in THF;4-Fluorobenzylzinc chloride, 0.5M solution in THF, AcroSeal;(4-fluorobenzyl)zinc(II) chloride;4-Fluorobenzylzinc chloride solution 0.5 M in THF;4-Fluorobenzylzinc chloride, 0.5M in THF, packaged under Argon in resealable ChemSeal™
    3. CAS NO:312693-07-5
    4. Molecular Formula: C7H6ClFZn
    5. Molecular Weight: 209.96
    6. EINECS: N/A
    7. Product Categories: Alkyl;Organozinc Halides;Reike and Organozinc Reagents
    8. Mol File: 312693-07-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: 1 °F
    4. Appearance: Yellow to orange to brown/Solution
    5. Density: 0.952 g/mL at 25 °C
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. Sensitive: Air Sensitive
    10. CAS DataBase Reference: 4-FLUOROBENZYLZINC CHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-FLUOROBENZYLZINC CHLORIDE(312693-07-5)
    12. EPA Substance Registry System: 4-FLUOROBENZYLZINC CHLORIDE(312693-07-5)
  • Safety Data

    1. Hazard Codes: F,Xn
    2. Statements: 11-14-19-22-36/37/38-40-36/37
    3. Safety Statements: 16-26-33-36/37/39-45-36/37
    4. RIDADR: UN 2056 3/PG 2
    5. WGK Germany: 1
    6. RTECS:
    7. HazardClass: 4.3
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 312693-07-5(Hazardous Substances Data)

312693-07-5 Usage

Uses

Used in Organic Synthesis:
4-Fluorobenzylzinc chloride is used as a reagent for the formation of carbon-carbon bonds. It is particularly effective in the Barbier reaction, where it adds to various electrophiles, such as carbonyl compounds, to create new carbon-carbon bonds.
Used in Functionalization of Organic Molecules:
4-Fluorobenzylzinc chloride is utilized as a convenient and efficient method for the functionalization of organic molecules. Its ability to form carbon-carbon bonds makes it a valuable tool in synthetic chemistry, allowing for the creation of a wide range of complex organic compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 312693-07-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,6,9 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 312693-07:
(8*3)+(7*1)+(6*2)+(5*6)+(4*9)+(3*3)+(2*0)+(1*7)=125
125 % 10 = 5
So 312693-07-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F.ClH.Zn/c1-6-2-4-7(8)5-3-6;;/h2-5H,1H2;1H;/q;;+1/p-1/rC7H6ClFZn/c8-10-5-6-1-3-7(9)4-2-6/h1-4H,5H2

312693-07-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (H58847)  4-Fluorobenzylzinc chloride, 0.5M in THF, packaged under Argon in resealable ChemSeal? bottles   

  • 312693-07-5

  • 50ml

  • 2075.0CNY

  • Detail
  • Aldrich

  • (498602)  4-Fluorobenzylzincchloridesolution  0.5 M in THF

  • 312693-07-5

  • 498602-50ML

  • 2,230.02CNY

  • Detail

312693-07-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Chloro(4-fluorobenzyl)zinc

1.2 Other means of identification

Product number -
Other names 4-fluorophenylzinc chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:312693-07-5 SDS

312693-07-5Relevant articles and documents

Continuous preparation method of benzyl zinc halide and derivatives of benzyl zinc halide

-

Paragraph 0039-0077, (2019/12/25)

The invention provides a continuous preparation method of benzyl zinc halide and derivatives of the benzyl zinc halide. According to the continuous preparation method, a continuous reactor is adoptedfor the reaction that zinc atoms are directly insert int

Polyfunctional benzylic zinc chlorides by the direct insertion of magnesium into benzylic chlorides in the presence of LiCl and ZnCl2

Metzger, Albrecht,Piller, Fabian M.,Knochel, Paul

, p. 5824 - 5826 (2009/04/13)

Benzylic zinc chlorides bearing various functional groups are smoothly prepared by the direct insertion of magnesium into benzylic chlorides in the presence of LiCl and ZnCl2. The Royal Society of Chemistry.

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