3155-30-4

Basic information

• Product Name: Benzaldehyde, 4-(dimethylamino)-, (4-nitrophenyl)hydrazone
• CAS NO: 3155-30-4
• Molecular Formula: C15H16N4O2
• Molecular Weight: 284.318
• Mol File: 3155-30-4.mol

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-(dimethylamino)-, (4-nitrophenyl)hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-(dimethylamino)-, (4-nitrophenyl)hydrazone(3155-30-4)
• EPA Substance Registry System: Benzaldehyde, 4-(dimethylamino)-, (4-nitrophenyl)hydrazone(3155-30-4)

Safety Data

• Hazardous Substances Data: 3155-30-4(Hazardous Substances Data)

Upstream product

• 100-10-7 4-dimethylamino-benzaldehyde 
• 100-16-3 4-nitrophenylhydrazone 

Downstream Products

• 78893-12-6 1-(p-Nitro-phenyl)-3-(p-N,N-dimethylamino-phenyl)-1,2,4-triazolo<4,3-a>pyridiniumperchlorat 
• 115095-29-9 p-nitro<((p-(N,N-dimethylamino)phenyl)-4-imidazolylmethyl)azo>benzene 
• 115095-18-6 3-(4-Dimethylamino-phenyl)-5-methyl-1-(4-nitro-phenyl)-1H-[1,2,4]triazolo[4,3-a]pyridin-4-ylium; perchlorate 
• 115095-20-0 3-(4-Dimethylamino-phenyl)-7-methyl-1-(4-nitro-phenyl)-1H-[1,2,4]triazolo[4,3-a]pyridin-4-ylium; perchlorate 
• 115095-30-2 p-nitro<((p-(N,N-dimethylamino)phenyl)-3-(1,2,4-triazolyl)methyl)azo>benzene 
• 107426-16-4 1-(p-N,N-Dimethylaminophenyl)-3-(p-nitrophenyl)-1,2,4-triazolo<4,3-a>chinoliniumperchlorat 
• 115095-26-6 3-(4-Dimethylamino-phenyl)-1-(4-nitro-phenyl)-1H-[1,2,4]triazolo[3,4-a]isoquinolin-4-ylium; perchlorate 
• 115095-24-4 7-Acetyl-3-(4-dimethylamino-phenyl)-1-(4-nitro-phenyl)-1H-[1,2,4]triazolo[4,3-a]pyridin-4-ylium; perchlorate 
• 115095-22-2 7-Cyano-3-(4-dimethylamino-phenyl)-1-(4-nitro-phenyl)-1H-[1,2,4]triazolo[4,3-a]pyridin-4-ylium; perchlorate 
• 115095-28-8 15-(4-Dimethylamino-phenyl)-17-(4-nitro-phenyl)-17H-16,17-diaza-14-azonia-cyclopenta[a]phenanthrene; perchlorate 
• 115117-28-7 Dimethyl-[4-(p-tolylamino-methylene)-cyclohexa-2,5-dienylidene]-ammonium; perchlorate 
• 15485-29-7 4-dimethylamino-benzaldehyde-(4-bromo-phenylimine) 
• 38131-68-9 4-(4-dimethylaminobenzylidene)aminoacetophenone 
• 15486-62-1 4-chloro-N-(4-dimethylaminobenzylidene)aniline 

Relevant articles and documents

Arylaldehydes-pentafluorophenyl hydrazones as second-order nonlinear optical chromophores: A novel approach for remarkably defeating the nonlinearity-transparency trade-off

A series of new arylhydrazone chromophores containing pentafluorophenyl as electronic acceptor are synthesized and found to exhibit significantly blue-shifted absorption in comparison with the corresponding 4-nitrophenyl analogues while keeping β value in

Diaryl hydrazones as multifunctional inhibitors of amyloid self-assembly

The design and application of an effective, new class of multifunctional small molecule inhibitors of amyloid self-assembly are described. Several compounds based on the diaryl hydrazone scaffold were designed. Forty-four substituted derivatives of this core structure were synthesized using a variety of benzaldehydes and phenylhydrazines and characterized. The inhibitor candidates were evaluated in multiple assays, including the inhibition of amyloid β (Aβ) fibrillogenesis and oligomer formation and the reverse processes, the disassembly of preformed fibrils and oligomers. Because the structure of the hydrazone-based inhibitors mimics the redox features of the antioxidant resveratrol, the radical scavenging effect of the compounds was evaluated by colorimetric assays against 2,2-diphenyl-1-picrylhydrazyl and superoxide radicals. The hydrazone scaffold was active in all of the different assays. The structure-activity relationship revealed that the substituents on the aromatic rings had a considerable effect on the overall activity of the compounds. The inhibitors showed strong activity in fibrillogenesis inhibition and disassembly, and even greater potency in the inhibition of oligomer formation and oligomer disassembly. Supporting the quantitative fluorometric and colorimetric assays, size exclusion chromatographic studies indicated that the best compounds practically eliminated or substantially inhibited the formation of soluble, aggregated Aβ species, as well. Atomic force microscopy was also applied to monitor the morphology of Aβ deposits. The compounds also possessed the predicted antioxidant properties; approximately 30% of the synthesized compounds showed a radical scavenging effect equal to or better than that of resveratrol or ascorbic acid.

Synthesis and properties of pyrazolino[60]fullerene-donor systems

A series of pyrazolino[60]fullerenes has been prepared in one pot by 1,3-dipolar cycloaddition to C60 of the corresponding nitrile imine, which was generated in situ from the corresponding hydrazone. A range of donors and acceptors were introdu

Photoelectric conversion from a nitrobenzene dye monolayer modified ITO electrode

An amphiphilic nitrobenzene dye (C18H37)2N-C6H 4-CH=N-NH-C6H4-NO2 has been synthesized and deposited on semiconducting transparent indium-tin oxide (ITO) electrodes by