Welcome to LookChem.com Sign In|Join Free


  • or


Post Buying Request

100-16-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

100-16-3 Usage

Chemical Properties

white to light yellow crystal powde


Different sources of media describe the Uses of 100-16-3 differently. You can refer to the following data:
1. Analytical reagent (aldehydes, ketones).
2. 4-Nitrophenylhydrazine is a nitro substituted aryl hydrazine with potential anticancer activity. Irritant.


ChEBI: A member of the class of phenylhydrazines that is phenylhydrazine substituted at the 4-position by a nitro group.

General Description

4-Nitrophenylhydrazine is a orange-red leaflet or needles wetted with water. 4-Nitrophenylhydrazine will emit toxic oxides of nitrogen when heated to decomposition. 4-Nitrophenylhydrazine is slightly heavier than water and insoluble in water. 4-Nitrophenylhydrazine may be irritating to skin, eyes and mucous membranes. 4-Nitrophenylhydrazine may be toxic by ingestion. 4-Nitrophenylhydrazine may be explosive and sensitive to friction in the dry state. 4-Nitrophenylhydrazine is used as a reagent for ketones and aliphatic aldehydes.

Reactivity Profile

4-NITROPHENYLHYDRAZINE is a powerful explosive. 4-Nitrophenylhydrazine can SELF-IGNITE in the presence of contaminants. Auto-ignition temperature may vary for 4-nitrophenylhydrazine similar to that of hydrazine which has an autoignition of as low as 74oC in contact with iron rust. Dangerous fire hazard or severe explosion can occur when exposed to heat, flame or oxidizing agents. Severe explosion may also occur by chemical reaction with alkali metals; BaO; CaO; K; Na; NH3; Cl2; chromates; CuO; Cu++ salts; F2; H2O2; iron rust; metallic oxides; PbO2;Ni; Ni(ClO4)2; HNO3; N2O; O2; liquid O2; K2Cr2O7; Na2Cr2O7; tetryl; zinc diamide; Zn(C2H5)2. Dangerous; when heated to decomposition 4-Nitrophenylhydrazine emits highly toxic nitrogen compounds; may explode by heat or chemical reaction. (Sax and Lewis, 1987) under Hydrazine p. 538-539.

Health Hazard

Some are toxic and may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution.

Safety Profile

Poison by intraperitoneal route.Mutation data reported. When heated to decomposition itemits toxic fumes of NOx. See also NITROCOMPOUNDS OF AROMATIC HYDROCARBONS

Purification Methods

Crystallise the hydrazine from EtOH. The hydrochloride has m 212o(dec) (from EtOH, also m 202-203o dec). [Beilstein 15 III 331, 15 IV 317.]

Check Digit Verification of cas no

The CAS Registry Mumber 100-16-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100-16:
13 % 10 = 3
So 100-16-3 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name 4-nitrophenylhydrazine

1.2 Other means of identification

Product number -
Other names Hydrazine, (4-nitrophenyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100-16-3 SDS

100-16-3Relevant articles and documents

Novel chemoselective reduction of aryldiazonium fluoroborates with Zn- NiCl2·6H2O-THF


, p. 714 - 715 (1999)

Substituted aryldiazonium fluoroborates are selectively reduced to the corresponding phenylhydrazines by using Zn-NiCl2·6H2O in THF as a reducing agent.



, p. 1929 (1967)




Paragraph 0202; 0211, (2020/01/24)

The present invention relates to substituted sulfonyl hydrazides that have the ability to inhibit lysine biosynthesis via the diaminopimelate pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibition of lysine biosynthesis is useful applications of this type include the use of the compound as herbicides and/or anti- bacterial agents.

Oxazolidinones compound and application thereof


Paragraph 0087;0091-0092, (2016/10/10)

The invention provides an oxazolidinones compound shown as the formula VI, or salt, an aquo-complex, or a crystal form of the oxazolidinones compound, which are pharmaceutically acceptable. The invention also provides a preparation method of the compound. In the current field of a chemical drug, activity of most compounds with changed structures becomes better, while toxicity is obviously enhanced, so that the compounds cannot be used as drugs. Compared with a compound in the prior art, the oxazolidinones compound provided in the invention has excellent anti-drug-resistance and antimicrobial activity. What is unexpected is that the oxazolidinones compound has better safety and benefits safe drug use and therapy of a patient.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 100-16-3