The compounds, pharmaceutical compositions, and methods of using such compounds or compositions thereof described herein are useful for treating a disease modulated by B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein expression.
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Page/Page column 94
(2010/04/03)
COMPOUNDS AND COMPOSITIONS AS HEDGEHOG PATHWAY MODULATORS
The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-fu
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(2009/09/05)
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