317806-88-5

Basic information

• Product Name: 4-[2-(4-NITRONAPHTHALEN-1-YLOXY)ETHYL]MORPHOLINE
• Synonyms: 4-[2-(4-NITRONAPHTHALEN-1-YLOXY)ETHYL]MORPHOLINE
• CAS NO: 317806-88-5
• Molecular Formula: C₁₆H₁₈N₂O₄
• Molecular Weight: 302.33
• Mol File: 317806-88-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-[2-(4-NITRONAPHTHALEN-1-YLOXY)ETHYL]MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-NITRONAPHTHALEN-1-YLOXY)ETHYL]MORPHOLINE(317806-88-5)
• EPA Substance Registry System: 4-[2-(4-NITRONAPHTHALEN-1-YLOXY)ETHYL]MORPHOLINE(317806-88-5)

Safety Data

• Hazardous Substances Data: 317806-88-5(Hazardous Substances Data)

Usage

Chemical structure

Consists of a morpholine ring attached to a 4-nitronaphthalene-1-yloxy group via a 2-carbon chain

Potential applications

Pharmaceuticals, novel materials, research and development for synthesis of new compounds

Handling and safety

Should be used with care in accordance with safe laboratory practices and regulations

Upstream product

• 605-62-9 4-nitro-1-naphthol 
• 3647-69-6 4-(2-chloroethyl)morpholine hydrochride 

Downstream Products

• 317806-90-9 4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-ylamine 
• 285983-48-4 BIRB-796 

Relevant articles and documents

2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME

A 2,3-dihydro-1H-indene-2-yl urea derivative represented by Formula (Ia) or a pharmaceutically acceptable salt thereof:

1,4-DISUBSTITUTED NAPHTALENES AS INHIBITORS OF P38 MAP KINASE

In general, the present invention relates to compounds capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating c

Microwave-assisted synthesis of N-pyrazole ureas and the p38α inhibitor BIRB 796 for study into accelerated cell ageing

Microwave irradiation of substituted hydrazines and β-ketoesters gives 5-aminopyrazoles in excellent yield, which can be transformed to the corresponding N-carbonyl derivatives by treatment with an isocyanate or chloroformate. Derivatization of 4-nitronaphth-1-ol using predominantly microwave heating methods and reaction with an N-pyrazole carbamate provides a rapid route to the N-pyrazole urea BIRB 796 in high purity, as a potent and selective inhibitor of p38α mitogen-activated protein kinase for the study of accelerated ageing in Werner syndrome cells. The Royal Society of Chemistry 2006.